Evidence map›Paper›PMID 33508519›Full record

ArticleAtherosclerosis2021

Increase in arterial stiffness measures after bariatric surgery.

Frances M Wang, Chao Yang, Hirofumi Tanaka, Josef Coresh, Chiadi E Ndumele, Kunihiro Matsushita

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Atherosclerosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Frances M WangJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Chao YangJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Hirofumi TanakaUniversity of Texas at Austin, Austin, TX, USA.
Josef CoreshJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Chiadi E NdumeleJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Kunihiro MatsushitaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: kuni.matsushita@jhu.edu.
Johns Hopkins University · USThe University of Texas at Austin · US

Funding

CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Elizabeth Selvin · 1985 to 2026
$17.5M
Elucidating the Role of Adipokines in Mediating and Predicting HF Associated with ObesityR01HL146907 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI NDUMELE, CHIADI E · 2019 to 2023
$4.0M
The Relationship of Obesity with Subclinical Myocardial Injury and Heart FailureK23HL122447 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI NDUMELE, CHIADI E · 2014 to 2018
$919k
NHLBI NIH HHS K23 HL122447NHLBI NIH HHS R01 HL146907NHLBI NIH HHS T32 HL007024
6 · The paper itself

Abstract

BACKGROUND AND

aimsThe relationship between obesity and arterial stiffness is complex, with a potential interaction by age (inverse association at younger age and positive at older age) and conflicting reports on the effect of lifestyle-based weight loss on arterial stiffness. Little is understood about post-bariatric surgery changes in arterial stiffness. This study aimed to examine post-bariatric surgery changes in arterial stiffness and identify factors associated with greater changes in arterial stiffness.

methodsIn 72 patients (mean age 44.5 years, 72.2% female), we evaluated two arterial stiffness measures, cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV), one month prior to and 6 months after bariatric surgery. Another follow-up visit was conducted 12 months after bariatric surgery in a subset of 58 participants.

resultsSix months after bariatric surgery, an evident decrease was seen in body mass index, heart rate, and systolic blood pressure. In contrast, both CAVI and haPWV significantly increased at 6 months (+0.64 [0.42, 0.87] and +0.24 [0.04, 0.44] m/s, respectively). Among 58 patients with relevant data, CAVI and haPWV remained elevated 12 months after bariatric surgery (+0.80 [0.53, 1.07] and +0.40 [0.17, 0.62] m/s, respectively). Being non-diabetic and having larger decreases in post-surgery heart rate were independently associated with greater increases in post-surgical CAVI.

conclusionsArterial stiffness measures, CAVI and haPWV, were elevated after bariatric surgery despite other favorable cardiometabolic changes. Further studies are necessary to elucidate the underlying mechanism and prognostic implications of this elevation in arterial stiffness measures after bariatric surgery.

Indexed as

Bariatric SurgeryVascular StiffnessAdultAgedAnkle Brachial IndexBlood PressureFemaleHumansMalePulse Wave AnalysisArterial stiffnessBariatric surgery outcomesCardio-ankle vascular indexObesityPulse wave velocity

Identifiers

PMID33508519
PMCPMC7935752
OpenAlexW3122278034

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.