ArticleCurrent biology : CB2021
A sex-specific switch between visual and olfactory inputs underlies adaptive sex differences in behavior.
Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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33 citing papers in PubMed, 74 citations in OpenAlex.
- Sex-biased expression of enteroendocrine cell-derived hormones contributes to higher fat storage ineLife · 2026Article
- Differential neuronal survival defines a novel axis of sexual dimorphism in the Drosophila brain.Cell genomics · 2026Article
- Organization and evolution of sex-biased gene expression inbioRxiv : the preprint server for biology · 2026Article
- Sociability is a Multidimensional Trait in Drosophila melanogaster.Behavior genetics · 2026Article
- Article
- High-resolution single-cell analyses reveal evolutionary constraints and evolvability of sexual circuits inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sexual dimorphism in the complete connectome of thebioRxiv : the preprint server for biology · 2025Article
- The Oviposition Inhibitory Neuron is a Potential Hub of Multi-Circuit Integration in theeNeuro · 2025Article
- Juvenile hormone regulates the maturation of sexually dimorphic naive ethanol olfactory preference inRoyal Society open science · 2025Article
- Sexually-dimorphic neurons in theResearch square · 2025Article
- Sexually-dimorphic neurons in thebioRxiv : the preprint server for biology · 2025Article
- Single-nucleus transcriptomics of wing sexual dimorphism and scale cell specialization in sulphur butterflies.PLoS biology · 2025Article
- High-resolution comparative single-cell transcriptomics ofbioRxiv : the preprint server for biology · 2025Article
- Lagging Brain Gene Expression Patterns of Drosophila melanogaster Young Adult Males Confound Comparisons Between Sexes.Molecular neurobiology · 2025Article
- Sex chromosomes and sex hormones differently shape microglial properties during normal physiological conditions in the adult mouse hippocampus.Journal of neuroinflammation · 2025Article
- Dedicated developmental programing for group-supporting behaviors in eusocial honeybees.Science advances · 2024Article
- Cellular sex throughout the organism underlies somatic sexual differentiation.Nature communications · 2024Article
- Article
- NeuronBridge: an intuitive web application for neuronal morphology search across large data sets.BMC bioinformatics · 2024Article
- Neuronal substrates of egg-laying behaviour at the abdominal ganglion of Drosophila melanogaster.Scientific reports · 2023Article
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8 authors at 2 institutions in 2 countries.
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Abstract
Although males and females largely share the same genome and nervous system, they differ profoundly in reproductive investments and require distinct behavioral, morphological, and physiological adaptations. How can the nervous system, while bound by both developmental and biophysical constraints, produce these sex differences in behavior? Here, we uncover a novel dimorphism in Drosophila melanogaster that allows deployment of completely different behavioral repertoires in males and females with minimum changes to circuit architecture. Sexual differentiation of only a small number of higher order neurons in the brain leads to a change in connectivity related to the primary reproductive needs of both sexes-courtship pursuit in males and communal oviposition in females. This study explains how an apparently similar brain generates distinct behavioral repertoires in the two sexes and presents a fundamental principle of neural circuit organization that may be extended to other species.
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