ArticleNeurourology and urodynamics2021
Prevalence of childhood trauma and its association with lower urinary tract symptoms in women and men in the LURN study.
Article in Neurourology and urodynamics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review exploring the relationship between sexual abuse and lower urinary tract symptoms.International urogynecology journal · 2023Pooled it
- Symptoms and subtypes of patients with lower urinary tract dysfunction - insights from the Symptoms of Lower Urinary Tract Dysfunction Research Network.Nature reviews. Urology · 2026Review
- Psychological and Behavioral Contributors to Lower Urinary Tract Dysfunction: Trauma, Stress, and Neurobiological Pathways.Current bladder dysfunction reports · 2026Review
- Urinary symptoms in sexual abuse survivors with severe post-traumatic morbidity: the impact of emotion regulation strategies.European journal of psychotraumatology · 2025Article
- Pathways from Adverse Childhood Family Environment to Lower Urinary Tract Symptoms and Impact Among Women.Journal of women's health (2002) · 2025Article
- Adverse Childhood Experiences and Lower Urinary Tract Symptoms and Impact Among Women.The Journal of urology · 2023Article
- The biopsychosocial impacts of anxiety on overactive bladder in women.Neurourology and urodynamics · 2023Article
- Childhood Sexual Abuse and Pelvic Floor Dysfunction in Midlife Women in the Study of Women's Health Across the Nation.Journal of women's health (2002) · 2023Observational
- Lower Urinary Tract Symptoms in Depression: A Review.Health psychology research · 2023Article
- Family Physician's Educational Interview with Patients Helps in Early Recognition of Lower Urinary Tract Symptoms.International journal of general medicine · 2021Article
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Authors and funding
11 authors.
Funding
Abstract
aimsTo describe the association between childhood traumas (death of a family member, severe illness, sexual trauma, parental separation) reported by women and men and lower urinary tract symptoms (LUTS).
methodsIn this secondary analysis of the Lower Urinary Tract Research Network Observational Cohort Study, participants completed the LUTS tool, childhood trauma events scale (CTES), PROMIS depression and anxiety and perceived stress scale. LUTS tool responses were combined to quantify urinary urgency, frequency, incontinence, and overall LUTS severity. Multivariable linear regression tested associations between trauma and LUTS; mental health scores were tested for potential mediation.
resultsIn this cohort (n = 1011; 520 women, 491 men), more women reported experiencing at least one trauma (75% vs. 64%, p < .001), greater than three traumas (26% vs. 15%, p < .001), and childhood sexual trauma (23% vs. 7%, p < .001), and reported higher impact from traumatic events compared with men (median [interquartile rnage] CTES score = 10 [5-15] vs. 6 [4-12], p < .001). The number of childhood traumatic events was not associated with severity of overall LUTS (p = .79), urinary frequency (p = .75), urgency (p = .61), or incontinence (p = .21). Childhood sexual trauma was significantly associated with higher incontinence severity (adjusted mean difference 4.5 points, 95% confidence interval= 1.11-7.88, p = .009). Mental health was a mediator between trauma and LUTS among those with at least one childhood trauma.
conclusionAlthough total childhood trauma is not associated with LUTS, childhood sexual trauma is associated with urinary incontinence severity. For patients with childhood trauma, half of the effect of CTE Impact score on overall LUTS severity is mediated through the association between trauma and the patient's mental health.
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