Evidence map›Paper›PMID 33507806›Full record

ArticleThe British journal of radiology2021

Multiparametric MR evaluation of uterine leiomyosarcoma and STUMP versus leiomyoma in symptomatic women planned for high frequency focussed ultrasound: accuracy of imaging parameters and interobserver agreement for identification of malignancy.

Parisa Aminzadeh, Ekaterina Alibrahim, Andrew Dobrotwir, Eldho Paul, Stacy Goergen

Open access · greenAbstract readComparative Study
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  9. Review
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  11. Leiomyoma with Bizarre Nuclei: A Current Update.International journal of women's health · 2022
    Review
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  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Parisa AminzadehRoyal Women's Hospital, Parkville, Victoria, Australia.
Ekaterina AlibrahimRoyal Women's Hospital, Parkville, Victoria, Australia.
Andrew DobrotwirRoyal Women's Hospital, Parkville, Victoria, Australia.
Eldho PaulDepartment of Epidemiology and Preventive Medicine, Monash University, Commercial Road, Prahran, Victoria, Australia.
Stacy GoergenRoyal Women's Hospital, Parkville, Victoria, Australia.
Royal Women's Hospital · AUMonash Health · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess accuracy of and interobserver agreement on multiparametric MR findings to distinguish uterine leiomyoma (LM) from uterine leiomyosarcoma (LMS) and soft tissue tumour of unknown malignant potential.

methodsInclusion criteria: All females over 18 years with least one uterine mass measuring 5 cm or more in at least one of the three standard orthogonal dimensions on MR with histopathological confirmation of LM, LMS, or soft tissue tumour of unknown malignant potential (STUMP) in the 3 months following MR. Patients with LMS were drawn from a larger cohort being assessed for MR-guided focussed ultrasound (MRgFUS) suitability. Image evaluation: Assessed variables were: lesion margin, margin definition, T2 signal homogeneity, >50% of lesion with T2 signal brighter than myometrium, haemorrhage, restricted diffusion, contrast enhancement (CE), CE pattern, local lymphadenopathy and ascites.

results32 LM, 10 LMS and 1 STUMP were evaluated. Ill-defined (

conclusionIrregular/ill-defined lesion margin best distinguished LMS/STUMP from LM with good interrater reliability. ADVANCES IN KNOWLEDGE: Assessment of agreement regarding MR parameters distinguishing LM from LMS and STUMP has not previously been undertaken in a cohort including a large number of patients with LMS. This will help inform evaluation of females considering minimally invasive LM treatment.

Indexed as

AdultCohort StudiesDiagnosis, DifferentialFemaleHigh-Intensity Focused Ultrasound AblationHumansLeiomyomaLeiomyosarcomaMiddle AgedMultiparametric Magnetic Resonance ImagingObserver VariationReproducibility of ResultsRetrospective StudiesSoft Tissue NeoplasmsUterine NeoplasmsUterus

Identifiers

PMID33507806
PMCPMC8011260
OpenAlexW3121294876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.