Evidence map›Paper›PMID 33507742›Full record

ArticleInorganic chemistry2021

Manganese(II)-Based Responsive Contrast Agent Detects Glucose-Stimulated Zinc Secretion from the Mouse Pancreas and Prostate by MRI.

Sara Chirayil, Veronica Clavijo Jordan, André F Martins, Namini Paranawithana, S James Ratnakar, A Dean Sherry

Open access · greenAbstract read
In one paragraph

Article in Inorganic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. ATP-responsive Mn(II)-basedChemical communications (Cambridge, England) · 2023
    Article
  4. MRI Methods for Imaging Beta-Cell Function in the Rodent Pancreas.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  5. Review
  6. Using micro-synchrotron radiation x-ray fluorescence (µ-SRXRF) for trace metal imaging in the development of MRI contrast agents for prostate cancer imaging.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2022
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sara ChirayilAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Veronica Clavijo JordanAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.ORCID http://orcid.org/0000-0002-1468-164X
André F MartinsAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.ORCID http://orcid.org/0000-0002-0171-0261
Namini ParanawithanaDepartment of Chemistry, University of Texas at Dallas, Richardson, Texas 75080, United States.
S James RatnakarAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
A Dean SherryAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.ORCID http://orcid.org/0000-0001-7150-8301
Southwestern Medical Center · USThe University of Texas at Dallas · USHarvard University · USSiemens (Germany) · DE

Funding

TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
Imaging Beta Cell Function in Vivo with Zinc Responsive MRI Contrast AgentsR01DK095416 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI SHERRY, DEAN · 2012 to 2021
$3.3M
Avance III HD (AV3) ConsoleS10OD023552 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI TAKAHASHI, MASAYA · 2017 to 2017
$600k
NIBIB NIH HHS P41 EB015908NIDDK NIH HHS R01 DK095416NIH HHS S10 OD023552
6 · The paper itself

Abstract

A Mn(II)-based zinc-sensitive MRI contrast agent, MnPyC3A-BPEN, was prepared, characterized, and applied in imaging experiments to detect glucose-stimulated zinc secretion (GSZS) from the mouse pancreas and prostate

Indexed as

AnimalsContrast MediaGlucoseMagnetic Resonance ImagingMaleManganeseMicePancreasProstateTissue DistributionZincContrast MediaGlucoseManganeseZinc

Identifiers

PMID33507742
PMCPMC8112388
OpenAlexW3125395347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.