ArticleJournal of clinical hypertension (Greenwich, Conn.)2021
Impact of gestational hypertension and preeclampsia on low birthweight and small-for-gestational-age infants in China: A large prospective cohort study.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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44 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Hypertensive disorders of pregnancy may increase the risk of neurodevelopmental delay in the offspring: a systematic review with meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Pooled it
- Effects of the Supplementation ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Gestational Hypertension as a Mediator of Prenatal Ozone Exposure and Term Low Birth Weight: Birth Cohort Study.JMIR public health and surveillance · 2026Article
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- Risk factors for neonatal brain injury in neonates born to mothers with preeclampsia: a retrospective study.BMC pregnancy and childbirth · 2026Article
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- Comparative maternal-fetal outcomes associated with different antihypertensive treatment strategies in preeclampsia: a retrospective cohort study.Frontiers in pharmacology · 2026Article
- Trimester-specific gestational weight gain and adverse outcomes in GDM women: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- The First 1000 Critical Days: Determinants of Adverse Birth Outcomes in the Sari Birth Cohort, Iran.International journal of preventive medicine · 2026Article
- Hypertensive disorders of pregnancy: incidence, anthropometric, hemodynamic, and urinary trajectories in a Colombian cohort.Frontiers in physiology · 2026Article
- Association between triglyceride-glucose index, placental inflammatory cytokines, and perinatal outcomes in preeclampsia.Frontiers in endocrinology · 2026Article
- The association of maternal serum parameters with pregnancy induced hypertension in Chinese population.PloS one · 2026Observational
- Adverse Materno-Foetal Outcomes of Pre-Eclampsia at a Rural Tertiary Hospital in the Eastern Cape Province of South Africa.International journal of environmental research and public health · 2025Article
- Sex-specific associations between hypertensive disorders in pregnancy and fetal and placental weight.Pediatric investigation · 2025Article
- Unveiling the risks and outcomes of preeclampsia: a case-control study in the UAE.BMC pregnancy and childbirth · 2025Article
- Baicalin alleviates HScientific reports · 2025Article
- Prediction of birthweight with early and mid-pregnancy antenatal markers utilising machine learning and explainable artificial intelligence.Scientific reports · 2025Article
- Predicting Low Birth Weight in Big Cities in the United States Using a Machine Learning Approach.International journal of environmental research and public health · 2025Article
- A Review of the Diagnosis, Risk Factors, and Role of Angiogenetic Factors in Hypertensive Disorders of Pregnancy.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Insights into the role of miR-877 and histidine-rich glycoprotein in preeclampsia.Archives of medical science : AMS · 2025Article
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8 authors at 1 institution in 1 country.
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Abstract
Studies have shown that maternal blood pressure level is associated with neonatal birthweight, but the results are not exactly consistent. As the most common hypertensive disorders during pregnancy, the mechanism of gestational hypertension and pre-eclampsia that affect fetal growth remain unclear. Our objective was to examine the association of gestational hypertension and pre-eclampsia with the risk of low birthweight (LBW) and small-for-gestational-age (SGA). Data were obtained from the China-US Collaborative Project for Neural Tube Defects Prevention, a large population-based cohort study. We selected participants who were registered in two southern provinces, had exact information on gestational blood pressure and pregnancy outcomes, and were not affected by chronic hypertension. Logistic regression was used to adjust for the effects of the main potential confounders, including age, body mass index, education, occupation, ethnicity, folic acid use, and parity. The overall incidences of LBW and SGA were 2.25% and 5.86%, respectively. The incidences of LBW/SGA were 3.58%/7.58% and 6.02%/10.67% for gestational hypertension and pre-eclampsia group, relative to 2.11%/5.68% and 2.16%/5.74% for normal group. The adjusted odds ratios associated with gestational hypertension/pre-eclampsia were 1.77 (95% CI: 1.63, 1.92)/3.01 (95% CI: 2.67, 3.40) for LBW and 1.40 (95% CI: 1.32, 1.48)/2.02 (95% CI: 1.84, 2.22) for SGA, respectively. The early onset of gestational hypertension/pre-eclampsia appeared to be a relatively more detrimental exposure window for both LBW and SGA. Our results support an association between gestational hypertension or pre-eclampsia and the increased risk of LBW and SGA.
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