Evidence map›Paper›PMID 33507591›Full record

ArticleMagnetic resonance in medicine2021

Reproducibility of

Benjamin J Pippard, Mary A Neal, Adam M Maunder, Kieren G Hollingsworth, Alberto Biancardi, Rod A Lawson, Holly Fisher, John N S Matthews, A John Simpson, Jim M Wild and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. DynamicJHLT open · 2025
    Article
  4. Reproducibility ofMagnetic resonance in medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Benjamin J PippardNewcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.
Mary A NealNewcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-5634-7586
Adam M MaunderPOLARIS, Department of IICD, University of Sheffield, Royal Hallamshire Hospital, Sheffield, United Kingdom.ORCID 0000-0002-1161-8741
Kieren G HollingsworthNewcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.
Alberto BiancardiPOLARIS, Department of IICD, University of Sheffield, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Rod A LawsonRespiratory Medicine, Sheffield Teaching Hospitals National Health Service Foundation Trust, Sheffield, United Kingdom.
Holly FisherPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
John N S MatthewsPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
A John SimpsonTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-4731-7294
Jim M WildPOLARIS, Department of IICD, University of Sheffield, Royal Hallamshire Hospital, Sheffield, United Kingdom.ORCID 0000-0002-7246-8660
Peter E ThelwallNewcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0003-1795-6394
Newcastle University · GBRoyal Hallamshire Hospital · GBNational Health Service · GB

Funding

British Heart Foundation SP/14/6/31350Medical Research Council G1100160Medical Research Council MR/M008894/1Medical Research Council MR/N018915/1Medical Research Council Capital Infrastructure award MR/M008894/1Medical Research Council Developmental Pathways Funding Scheme award MR/N018915/1
6 · The paper itself

Abstract

purposeTo assess the reproducibility of percentage ventilated lung volume (%VV) measurements in healthy volunteers acquired by fluorine (

methodsIn this prospective, ethically approved study, 40 healthy participants were recruited (May 2018-June 2019) to one of two research sites. Participants underwent a single MRI scan session on a 3T scanner, involving periodic inhalation of a 79% perfluoropropane/21% oxygen gas mixture. Each gas inhalation session lasted about 30 seconds, consisting of three deep breaths of gas followed by a breath-hold. Four

resultsThe MRI scans were well tolerated throughout, with no adverse events. There was a high degree of consistency in %VV measurements for each participant (CoV

conclusionWe demonstrate good reproducibility of %VV measurements in a group of healthy participants using

Indexed as

FluorineAdultAgedContrast MediaFemaleFluorocarbonsHumansLungLung Volume MeasurementsMagnetic Resonance ImagingMaleMiddle AgedObserver VariationProspective StudiesReproducibility of ResultsYoung AdultContrast MediaFluorineFluorocarbonsperflutren19F-MRIlungperfluoropropanereproducibilityventilation

Identifiers

PMID33507591
PMCPMC7986730
OpenAlexW3112523150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.