Evidence map›Paper›PMID 33507308›Full record

ArticleThe Journal of infectious diseases2021

Projected HIV and Bacterial Sexually Transmitted Infection Incidence Following COVID-19-Related Sexual Distancing and Clinical Service Interruption.

Samuel M Jenness, Adrien Le Guillou, Christina Chandra, Laura M Mann, Travis Sanchez, Daniel Westreich, Julia L Marcus

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A Review of Network Models for HIV Spread.Journal of acquired immune deficiency syndromes (1999) · 2025
    Pooled it
  3. Article
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  5. Decreased chlamydia notifications in six European Union/European Economic Area countries and England, 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Article
  6. Article
  7. COVID-19-Related Diminished Peer HIV Communication Intentions Among Sexual and Gender Expansive Individuals in Kazakhstan.Health education & behavior : the official publication of the Society for Public Health Education · 2026
    Article
  8. Article
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  11. The Future of HIV: Challenges in meeting the 2030medRxiv : the preprint server for health sciences · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Samuel M JennessDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Adrien Le GuillouDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Christina ChandraDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Laura M MannDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Travis SanchezDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Daniel WestreichDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA.
Julia L MarcusDepartment of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
EpiModel 2.0: Integrated Network Models for HIV/STI Prevention ScienceR01AI138783 · NIAID · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2018 to 2021
$3.0M
Optimizing Care for HIV/HCV-Coinfected Patients in the New HCV Treatment EraK01AI122853 · NIAID · KAISER FOUNDATION RESEARCH INSTITUTE · PI MARCUS, JULIA L. · 2016 to 2020
$655k
NIAID NIH HHS K01 AI122853NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI138783
6 · The paper itself

Abstract

backgroundThe global COVID-19 pandemic has the potential to indirectly impact transmission dynamics and prevention of HIV and other sexually transmitted infections (STI). It is unknown what combined impact reductions in sexual activity and interruptions in HIV/STI services will have on HIV/STI epidemic trajectories.

methodsWe adapted a model of HIV, gonorrhea, and chlamydia for a population of approximately 103 000 men who have sex with men (MSM) in the Atlanta area. Model scenarios varied the timing, overlap, and relative extent of COVID-19-related sexual distancing and service interruption within 4 service categories (HIV screening, preexposure prophylaxis, antiretroviral therapy, and STI treatment).

resultsA 50% relative decrease in sexual partnerships and interruption of all clinical services, both lasting 18 months, would generally offset each other for HIV (total 5-year population impact for Atlanta MSM, -227 cases), but have net protective effect for STIs (-23 800 cases). If distancing lasted only 3 months but service interruption lasted 18 months, the total 5-year population impact would be an additional 890 HIV cases and 57 500 STI cases.

conclusionsImmediate action to limit the impact of service interruptions is needed to address the indirect effects of the global COVID-19 pandemic on the HIV/STI epidemic.

Indexed as

COVID-19GeorgiaHIV InfectionsHomosexuality, MaleHumansIncidenceMaleModels, StatisticalPandemicsSexual and Gender MinoritiesSexual BehaviorSexually Transmitted Diseases, BacterialSexual PartnersCOVID-19HIVmathematical modelmen who have sex with mensexual networksSTI

Identifiers

PMID33507308
PMCPMC7928867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.