Evidence map›Paper›PMID 33506736›Full record

ArticleJournal of managed care & specialty pharmacy2021

The effectiveness and value of novel treatments for cystic fibrosis.

Jeffrey A Tice, Karen M Kuntz, Kael Wherry, Matt Seidner, David M Rind, Steven D Pearson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of managed care & specialty pharmacy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Tobacco smoke exposure is associated with diminished longitudinal benefit of elexacaftor/tezacaftor/ivacaftor in cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jeffrey A TiceDivision of General Internal Medicine, University of California, San Francisco.
Karen M KuntzSchool of Public Health, University of Minnesota.
Kael WherrySchool of Public Health, University of Minnesota.
Matt SeidnerInstitute for Clinical and Economic Review, Boston, MA.
David M RindInstitute for Clinical and Economic Review, Boston, MA.
Steven D PearsonInstitute for Clinical and Economic Review, Boston, MA.
University of Minnesota · USInstitute for Clinical and Economic Review · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cost-Benefit AnalysisModels, EconomicAdolescentAminophenolsAminopyridinesBenzodioxolesChildChloride Channel AgonistsCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDrug ApprovalDrug CombinationsDrug CostsHealth PolicyHumansIndolesAminophenolsAminopyridinesBenzodioxolesCFTR protein, humanChloride Channel AgonistsCystic Fibrosis Transmembrane Conductance RegulatorDrug Combinationselexacaftor, ivacaftor, tezacaftor drug combinationIndolesivacaftorlumacaftor, ivacaftor drug combinationPyrazolesPyridinesQuinolinesQuinolonestezacaftor, ivacaftor drug combination

Identifiers

PMID33506736
PMCPMC10391049
OpenAlexW3124331096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.