Evidence map›Paper›PMID 33506683›Full record

ArticleJournal of the American Heart Association2021

Characteristics and Outcomes of Elderly Patients With Hypertrophic Cardiomyopathy.

Alaa Alashi, Nicholas G Smedira, Zoran B Popovic, Agostina Fava, Maran Thamilarasan, Samir R Kapadia, Per Wierup, Harry M Lever, Milind Y Desai

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Aging Heart: A Molecular and Clinical Challenge.International journal of molecular sciences · 2022
    Review
  14. Review
  15. Article
  16. Article
  17. An Unusual Case of Shock in an Octogenarian.Annals of geriatric medicine and research · 2021
    Article
  18. Article
  19. Article
  20. Hypertrophic Cardiomyopathy in the Elderly: A Case Identified With Genetic Screening.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Alaa AlashiHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Nicholas G SmediraHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Zoran B PopovicHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Agostina FavaHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Maran ThamilarasanHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Samir R KapadiaHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Per WierupHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Harry M LeverHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Milind Y DesaiHypertrophic Cardiomyopathy Center Heart and Vascular InstituteCleveland Clinic Cleveland OH.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background We report characteristics and outcomes of elderly patients with hypertrophic cardiomyopathy (HCM) with basal septal hypertrophy and dynamic left ventricular outflow tract obstruction. Methods and Results We studied 1110 consecutive elderly patients with HCM (excluding moderate or greater aortic stenosis or subaortic membrane, age 80±5 years [range, 75-92 years], 66% women), evaluated at our center between June 2002 and December 2018. Clinical and echocardiographic data, including maximal left ventricular outflow tract gradient, were recorded. The primary outcome was death and appropriate internal defibrillator discharge. Hypertension was observed in 72%, with a Society of Thoracic Surgeons (STS) score (8.6±6); while 80% had no HCM-related sudden cardiac death risk factors. Left ventricular mass index, basal septal thickness, and maximal left ventricular outflow tract gradient were 127±43 g/m

Indexed as

AgedAged, 80 and overCardiac Surgical ProceduresCardiomyopathy, HypertrophicEchocardiographyFemaleHeart SeptumHumansIncidenceMaleRisk FactorsSurvival RateUnited Stateselderlyhypertrophic cardiomyopathyoutcomes

Identifiers

PMID33506683
PMCPMC7955450
OpenAlexW3122099352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.