ArticleInternational journal of cancer2021
Contemporary management of breast cancer in Nigeria: Insights from an institutional database.
Article in International journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 5 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 5 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- 5-year survival rate and determinants of decreased survival among patients with breast cancer in Africa: a systematic review and meta-analysis.BMJ global health · 2026Pooled it
- Stage at Diagnosis and Molecular Subtype Distribution of Breast Cancer in Sub-Saharan Africa: A Systematic Review.Cancer reports (Hoboken, N.J.) · 2026Pooled it
- Survival Patterns Among Patients With Breast Cancer in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Breast Cancer Phenotypes in Africa: A Scoping Review and Meta-Analysis.JCO global oncology · 2023Pooled it
- Access to Radiation Therapy and Related Clinical Outcomes in Patients With Cervical and Breast Cancer Across Sub-Saharan Africa: A Systematic Review.JCO global oncology · 2023Pooled it
- Pragmatic Clinical Trial Assessing Response to Neoadjuvant Docetaxel and Trastuzumab in Nigerian Women With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer (ARETTA).JCO global oncology · 2026Trial
- Trial
- Breast Cancer-Related Lymphedema: A Common Challenge among Nigerian Breast Cancer Survivors.Breast care (Basel, Switzerland) · 2026Article
- "…it is not the sickness itself that kills. It is the emotional trauma": a qualitative study of the lived experience and systemic barriers of women with breast cancer in Nigeria.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care: A Randomized Control Trial- COST-FIN.Research square · 2026Article
- Coping Strategies and Perception of Patients With Breast Cancer Post-Surgery in an Underserved Region of Nigeria.Psycho-oncology · 2026Article
- Quality of life of breast cancer patients: A comparative study of survivors and patients undergoing radiotherapy in Morocco.Journal of education and health promotion · 2026Article
- Age-specific patterns of breast cancer in Nigerian women unraveled through histological analysis.Scientific reports · 2025Article
- Breast cancer overall survival, annual risks of death, and survival gap apportionment in sub-Saharan Africa (ABC-DO): 7-year follow-up of a prospective cohort study.The Lancet. Global health · 2025Article
- Method of detection, determinants and subsequent treatments for breast, cervical and prostate cancers in Edo-Benin, Nigeria.Cancer causes & control : CCC · 2025Article
- Distribution of Immunohistochemical Subtypes of Breast Cancer in Nigeria: A Systematic Review.Cureus · 2025Review
- Current Status of Cancer Diagnosis and Treatment in Nigeria.Health science reports · 2025Article
- Knowledge and perceptions of genetic testing for patients with breast cancer in Nigeria: a survey of healthcare providers.Hereditary cancer in clinical practice · 2025Article
- Psychosocial wellbeing of patients with breast cancer following surgical treatment in Northern Nigeria.BMC psychiatry · 2025Article
- Health Care Professional Adherence to Breast Cancer Management Guidelines in Nigeria.JAMA network open · 2025Article
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Authors and funding
18 authors at 5 institutions in 3 countries.
Funding
Abstract
High-quality data are needed to guide interventions aimed at improving breast cancer outcomes in sub-Saharan Africa. We present data from an institutional breast cancer database to create a framework for cancer policy and development in Nigeria. An institutional database was queried for consecutive patients diagnosed with breast cancer between January 2010 and December 2018. Sociodemographic, diagnostic, histopathologic, treatment and outcome variables were analyzed. Of 607 patients, there were 597 females with a mean age of 49.8 ± 12.2 years. Most patients presented with a palpable mass (97%) and advanced disease (80.2% ≥ Stage III). Immunohistochemistry was performed on 21.6% (131/607) of specimens. Forty percent were estrogen receptor positive, 32.8% were positive for HER-2 and 43.5% were triple negative. Surgery was performed on 49.9% (303/607) of patients, while 72% received chemotherapy and 7.9% had radiotherapy. At a median follow-up period of 20.5 months, the overall survival was 43.6% (95% CI -37.7 to 49.5). Among patients with resectable disease, 18.8% (57/303) experienced a recurrence. Survival was significantly better for early-stage disease (I and II) compared to late-stage disease (III or IV) (78.6% vs 33.3%, P < .001). Receipt of adjuvant radiotherapy after systemic chemotherapy was associated with improved survival in patients with locally advanced disease (68.5%, CI -46.3 to 86 vs 51%, CI 38.6 to 61.9, P < .001). This large cohort highlights the dual burden of advanced disease and inadequate access to comprehensive breast cancer care in Nigeria. There is a significant potential for improving outcomes by promoting early diagnosis and facilitating access to multimodality treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.