Evidence map›Paper›PMID 33506429›Full record

ArticleClinical oral investigations2021

Periodontitis related to cardiovascular events and mortality: a long-time longitudinal study.

Viveca Wallin Bengtsson, Gösta Rutger Persson, Johan Sanmartin Berglund, Stefan Renvert

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05741970 (Interaction Between Hypertension and Periodontitis), which is not on this map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05741970 nacompletednot on this map

Interaction Between Hypertension and Periodontitis

TypeinterventionalSponsorGazi UniversityRan2017 to 2018Enrolled42ConditionsHypertension, PeriodontitisArmsScaling and root planing
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 4 countries.

Viveca Wallin BengtssonUniversity of Kristianstad, Elmetorpsvägen 15, 29188, Kristianstad, Sweden. viveca.wallin_bengtsson@hkr.se.ORCID https://orcid.org/0000-0002-8092-665X
Gösta Rutger PerssonUniversity of Kristianstad, Elmetorpsvägen 15, 29188, Kristianstad, Sweden.ORCID https://orcid.org/0000-0002-3620-5978
Johan Sanmartin BerglundDepartment of Health, Blekinge Institute of Technology, Karlskrona, Sweden.ORCID https://orcid.org/0000-0003-4312-2246
Stefan RenvertUniversity of Kristianstad, Elmetorpsvägen 15, 29188, Kristianstad, Sweden.ORCID https://orcid.org/0000-0003-0992-2362
Kristianstad University · SELund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study assessed if individuals ≥ 60 years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17 years. MATERIAL AND

methodsAt baseline individuals ≥ 60 received a dental examination including a panoramic radiograph. Periodontitis was defined as having ≥ 30% sites with ≥ 5-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered.

resultsAssociations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60-93 years (HR: 1.5, CI: 1.1-2.1, p = 0.017), in women (HR: 2.1, CI: 1.3-3.4, p = 0.002), and in individuals 78-96 years (HR: 1.7, CI: 1.0-2.6, p = 0.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2-1.8, p = 0.002), specifically in men (HR: 1.5, CI: 1.1-1.9, p = 0.006) or in ages 60-72 years (HR: 2.2, CI: 1.5-3.2, p = 0.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3-2.4, p = 0.000).

conclusionsIndividuals with periodontitis have an increased risk for future events of ischemic heart diseases and death. CLINICAL RELEVANCE: Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.

Indexed as

PeriodontitisStrokeAdolescentAgedFemaleFollow-Up StudiesHumansIncidenceLongitudinal StudiesMaleMiddle AgedRisk FactorsEpidemiologyIschemic heart diseaseMortalityPeriodontitis

Identifiers

PMID33506429
PMCPMC8137476
OpenAlexW3096936386

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.