Evidence map›Paper›PMID 33506336›Full record

ArticleAnalytical and bioanalytical chemistry2021

Variability in hair gadolinium concentrations among decedents who received gadolinium-based contrast agents.

Brianne R Duncan, Makoto Hasegawa, Desiree A Marshall, Luis F Gonzalez-Cuyar, Michael Paulsen, Masahiro Kobayashi, Kenneth R Maravilla, Christopher D Simpson

Open access · greenAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Brianne R DuncanDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, 98195, USA. bduncan@exponent.com.ORCID http://orcid.org/0000-0003-4872-6102
Makoto HasegawaDepartment of Radiology, University of Washington, Seattle, WA, 98195, USA.
Desiree A MarshallDepartment of Pathology, University of Washington School of Medicine, Seattle, WA, 98195, USA.
Luis F Gonzalez-CuyarDepartment of Pathology, University of Washington School of Medicine, Seattle, WA, 98195, USA.
Michael PaulsenDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, 98195, USA.
Masahiro KobayashiDepartment of Radiology, University of Washington, Seattle, WA, 98195, USA.
Kenneth R MaravillaRadiology & Neurological Surgery, University of Washington, Seattle, WA, 98195, USA.
Christopher D SimpsonDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, 98195, USA.
University of Washington · USExponent (United States) · USToho University · JP

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
NIEHS NIH HHS P30 ES007033NIEHS NIH HHS P30ES007033
6 · The paper itself

Abstract

This study utilized laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to quantify gadolinium in the hair of autopsy cases that had received gadolinium-based contrast agents (GBCAs) before death. Consecutive autopsy cases were reviewed for GBCA injections and subjects who received a single type of GBCA in the year before death were included. Hair samples were analyzed using LA-ICP-MS as a line scan technique and parameters were optimized to maximize instrument sensitivity, accuracy, and precision. Linear regression analyses between hair measures and gadolinium dose were executed. LA-ICP-MS analysis produced a time-resolved record of GCBA exposure, with the position of the gadolinium peak maxima along the hair shaft providing a good estimate for the day that GBCA injection occurred (R

Indexed as

AdultAgedAutopsyBrainContrast MediaFemaleGadoliniumGlomerular Filtration RateHairHumansLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsReproducibility of ResultsContrast MediaGadoliniumBiomonitoringGadoliniumGBCAHairLA-ICP-MSPostmortem

Identifiers

PMID33506336
PMCPMC10537202
OpenAlexW3121563362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.