Evidence map›Paper›PMID 33506313›Full record

ArticleAging clinical and experimental research2021

SARC-F as a case-finding tool for sarcopenia according to the EWGSOP2. National validation and comparison with other diagnostic standards.

Karolina Piotrowicz, Anna Głuszewska, Joanna Czesak, Małgorzata Fedyk-Łukasik, Ewa Klimek, Dolores Sánchez-Rodríguez, Anna Skalska, Barbara Gryglewska, Tomasz Grodzicki, Jerzy Gąsowski

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04757454 (Performance Indicators of the SARC-F Questionnaire in Acute Care), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04757454 completednot on this map

Performance Indicators of the SARC-F Questionnaire in Acute Care

TypeobservationalSponsorBrugmann University HospitalRan2019 to 2020Enrolled105ConditionsSarcopenia, Sensitivity, Old Age, DebilityArms5-item SARC-F questionnaire
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. [Suspicion of sarcopenia as a predictor of toxicity in older people with cancer].Revista medica del Instituto Mexicano del Seguro Social · 2026
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  3. Effects of early surgery (within 48 hours)Journal of thoracic disease · 2026
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  20. Challenges in the Management of Sarcopenia in the Primary Care Setting: A Scoping Review.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Karolina PiotrowiczDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Anna GłuszewskaDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Joanna CzesakDepartment of Internal Medicine and Geriatrics, University Hospital, Kraków, Poland.
Małgorzata Fedyk-ŁukasikDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Ewa KlimekDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Dolores Sánchez-RodríguezDivision of Public Health, Epidemiology and Health Economics, WHO Collaborating Centre for Public Health Aspects of Musculo-Skeletal Health and Ageing, University of Liège, Liège, Belgium.
Anna SkalskaDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Barbara GryglewskaDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Tomasz GrodzickiDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland.
Jerzy GąsowskiDepartment of Internal Medicine and Gerontology, Faculty of Medicine, Medical College, Jagiellonian University, Ul. Jakubowskiego 2, 30-688, Kraków, Poland. jerzy.gasowski@uj.edu.pl.ORCID http://orcid.org/0000-0002-8025-5323
Jagiellonian University · PLUniversity of Liège · BEUniversity School of Physical Education in Kraków · PL

Funding

Uniwersytet Jagielloński Collegium Medicum K/ZDS/007805
6 · The paper itself

Abstract

backgroundSarcopenia is a potentially reversible condition, which requires proper screening and diagnosis.

aimsTo validate a Polish version of sarcopenia screening questionnaire (SARC-F), and assess its clinical performance.

methodsCross-sectional validation study in community-dwelling subjects ≥ 65 years of age. Diagnosis of sarcopenia was based on the 2018 2nd European Working Group on Sarcopenia in Older People (EWGSOP2) consensus. Hand grip and 4-m gait speed were measured, and the Polish version of SARC-F was administered.

resultsThe mean (SD) age of 73 participants (21.9% men) was 77.8 (7.3) years. Seventeen participants (23.3%) fulfilled the EWGSOP2 criteria of sarcopenia, and 9 (12.3%) criteria for severe sarcopenia. Fourteen (19.2%) participants fulfilled the SARC-F criteria for clinical suspicion of sarcopenia. The Cronbach's alpha coefficient for internal was 0.84. With EWGSOP2 sarcopenia as a gold standard, the sensitivity of SARC-F was 35.3% (95% CI 14.2-61.7, p = 0.33), specificity was 85.7% (95% CI 73.8-93.6, p < 0.0001). The corresponding positive and negative predictive values were 42.9% (p = 0.79) and 81.4% (p < 0.0001), respectively. The probability of false-positive result was 14.3% (95% CI 6.4-26.2, p < 0.0001) and the probability of false-negative result was 64.7% (95% CI 38.3-85.8, p = 0.33). Overall the predictive power of SARC-F was low (c-statistic 0.64). DISCUSSION: SARC-F is currently recommended for sarcopenia case finding in general population of older adults. However, its sensitivity is low, despite high specificity.

conclusionsAt present SARC-F is better suited to rule out sarcopenia then to case-finding. Further refinement of screening for sarcopenia with the use of SARC-F seems needed.

Indexed as

SarcopeniaAgedCross-Sectional StudiesFemaleGeriatric AssessmentHand StrengthHumansMalePolandSurveys and QuestionnairesDXAEWGSOP2SARC-FSarcopeniaScreening

Identifiers

PMID33506313
PMCPMC8249283
OpenAlexW3126030972

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.