ArticleCommunications materials2021
Extended gate field-effect-transistor for sensing cortisol stress hormone.
Article in Communications materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 147 citations in OpenAlex.
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- Laser-induced graphene-based, flexible, and all-inorganic carbon thin-film transistor for non-invasive monitoring of cortisol.Mikrochimica acta · 2025Article
- Noninvasive On-Skin Biosensors for Monitoring Diabetes Mellitus.Nano-micro letters · 2025Review
- Next-Gen Point-of-Care Tool for Ultra-Sensitive Detection of Urinary Spermine for Prostate Cancer Diagnosis.ACS sensors · 2025Article
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- Effects of Walking and Barre Exercise on CES-D, Stress Hormones, hs-CRP, and Immunoglobulins in Elderly Women.Journal of clinical medicine · 2025Article
- Emerging Dual-Gate FET Sensor Paradigm for Ultra-Low Concentration Cortisol Detection in Complex Bioenvironments.Biosensors · 2025Article
- Sweat, tears, and beyond: advanced wearable sensors for personalized health and athletic performance.Frontiers in bioengineering and biotechnology · 2025Review
- Multi-Electrode Extended Gate Field Effect Transistors Based on Laser-Induced Graphene for the Detection of Vitamin C and SARS-CoV-2.ACS applied materials & interfaces · 2024Article
- Fully-Printed Sensor Based Extended Gate Field Effect Transistors for Wireless Monitoring of Potassium and Ammonium Ions.Proceedings of IEEE Sensors. IEEE International Conference on Sensors · 2024Article
- 2D Materials in Advanced Electronic Biosensors for Point-of-Care Devices.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Detection of α-Galactosidase A Reaction in Samples Extracted from Dried Blood Spots Using Ion-Sensitive Field Effect Transistors.Sensors (Basel, Switzerland) · 2024Article
- Ultrasensitive 3D Stacked Silicon Nanosheet Field-Effect Transistor Biosensor with Overcoming Debye Shielding Effect for Detection of DNA.Biosensors · 2024Article
- A physicochemical-sensing electronic skin for stress response monitoring.Nature electronics · 2024Article
- Exploring new scientific innovations in combating suicide: a stress detection wristband.The Pan African medical journal · 2024Article
- Surface-modified CMOS biosensors.Frontiers in bioengineering and biotechnology · 2024Review
- Field effect transistor based wearable biosensors for healthcare monitoring.Journal of nanobiotechnology · 2023Review
- Article
- Skin-Interfaced Wearable Sweat Sensors for Precision Medicine.Chemical reviews · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cortisol is a hormone released in response to stress and is a major glucocorticoid produced by adrenal glands. Here, we report a wearable sensory electronic chip using label-free detection, based on a platinum/graphene aptamer extended gate field effect transistor (EG-FET) for the recognition of cortisol in biological buffers within the Debye screening length. The device shows promising experimental features for real-time monitoring of the circadian rhythm of cortisol in human sweat. We report a hysteresis-free EG-FET with a voltage sensitivity of the order of 14 mV/decade and current sensitivity up to 80% over the four decades of cortisol concentration. The detection limit is 0.2 nM over a wide range, between 1 nM and 10 µM, of cortisol concentrations in physiological fluid, with negligible drift over time and high selectivity. The dynamic range fully covers those in human sweat. We propose a comprehensive analysis and a unified, predictive analytical mapping of current sensitivity in all regimes of operation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.