ReviewiScience2021
3D-printed microneedles in biomedical applications.
Review in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Efficacy of Intravenous Analgesia and Various Nerve Blocks for Pain Management in Elderly Patients With Hip Fractures: A Meta-Analysis.Orthopaedic surgery · 2025Pooled it
- Low-Shrinkage 3D-Printed Polymeric Microneedle Arrays with Electroless Silver Coating for Enhanced Thermal and Mechanical Performance in Dermatological Applications.Materials (Basel, Switzerland) · 2026Article
- Bilateral SERS-Microneedle Patch for Co-Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Octopus sucker-inspired, Turkish gall extract-integrated microneedle patch for oral ulcer mitigation.iScience · 2026Article
- Comparative Evaluation of Hydrogel Dip-Coating on Cone and Pyramid Microneedle Arrays Fabricated by LCD 3D Printing.Pharmaceutics · 2026Article
- A programmable bioresorbable electrochemical microneedle sensor array for perioperative monitoring of organ health.Nature biomedical engineering · 2026Article
- Evolution of 3D-Printed Microneedles toward Closed-Loop Theranostic Platforms.Research (Washington, D.C.) · 2026Review
- Integrating Polymeric 3D-Printed Microneedles with Wearable Devices: Toward Smart and Personalized Healthcare Solutions.Polymers · 2025Review
- In-Field Detection of Plant Pathogens Using Three-Dimensional-Printed Microneedles and a Portable Platform.ACS sensors · 2025Article
- Advances in 3D Printed Microneedles as a Prototype for Skin Targeted Therapeutics in Personalized Dermal Pharmaceuticals.AAPS PharmSciTech · 2025Review
- Bioprinting revolution: Innovative design of 3D bioactive scaffolds for living organs and transdermal tissues.Bioengineering & translational medicine · 2025Review
- Evolving transdermal therapeutics: a review on self-dissolving polymeric microneedlesRSC advances · 2025Review
- Microneedle patches: the next frontier in cardiovascular care.Drug delivery and translational research · 2025Review
- Nanoparticles-incorporated hydrogel microneedle for biomedical applications: Fabrication strategies, emerging trends and future prospects.Asian journal of pharmaceutical sciences · 2025Review
- Polymeric 3D-Printed Microneedle Arrays for Non-Transdermal Drug Delivery and Diagnostics.Polymers · 2025Review
- Article
- 3D printed microneedles: revamping transdermal drug delivery systems.Drug delivery and translational research · 2025Review
- Article
- Laser-based 3D printing and optical characterization of optical micro-nanostructures inspired by nocturnal insects compound eyes.Scientific reports · 2025Article
- Bridging the gap: how patient-derived lung cancer organoids are transforming personalized medicine.Frontiers in cell and developmental biology · 2025Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conventional needle technologies can be advanced with emerging nano- and micro-fabrication methods to fabricate microneedles. Nano-/micro-fabricated microneedles seek to mitigate penetration pain and tissue damage, as well as providing accurately controlled robust channels for administrating bioagents and collecting body fluids. Here, design and 3D printing strategies of microneedles are discussed with emerging applications in biomedical devices and healthcare technologies. 3D printing offers customization, cost-efficiency, a rapid turnaround time between design iterations, and enhanced accessibility. Increasing the printing resolution, the accuracy of the features, and the accessibility of low-cost raw printing materials have empowered 3D printing to be utilized for the fabrication of microneedle platforms. The development of 3D-printed microneedles has enabled the evolution of pain-free controlled release drug delivery systems, devices for extracting fluids from the cutaneous tissue, biosignal acquisition, and point-of-care diagnostic devices in personalized medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.