Evidence map›Paper›PMID 33506177›Full record

ArticleTherapeutic advances in ophthalmology

Alone laser versus bevacizumab plus laser for diffuse diabetic macular edema (ALBA randomized trial).

Alicia Pareja-Ríos, Elena de Armas-Ramos, Ana Aldea-Perona, Sergio Bonaque-González

Open access · diamondAbstract read
In one paragraph

Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alicia Pareja-RíosServicio de Oftalmología, Hospital Universitario de Canarias, C/Ofra s/n, 38320 San Cristóbal de La Laguna, Santa Cruz de Tenerife, Islas Canarias, Spain.ORCID https://orcid.org/0000-0001-5063-0412
Elena de Armas-RamosDepartment of Ophthalmology, University Hospital of the Canary Islands, San Cristóbal de La Laguna, Spain.
Ana Aldea-PeronaDepartment of Ophthalmology, University Hospital of the Canary Islands, San Cristóbal de La Laguna, Spain.
Sergio Bonaque-GonzálezWooptix S.L., San Cristóbal de La Laguna, Spain.
Hospital Universitario de Canarias · ESTiGenix (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo report the 12-month results of laser (treatment G1) versus intravitreal bevacizumab combined with laser (treatment G2) in patients with diffuse diabetic macular edema (DME).

methodsIn this single-center randomized independent controlled trial, 32 patients were randomized to G1 (

resultsG2 was superior to G1 improving best corrected visual acuity (BCVA) with respect baseline (+8.0 vs + 3.0;

conclusionG2 provided superior visual acuity gains over G1 in patients with visual impairment due to center-involving diffuse DME, associated with significant gains in VFQ-25 scores.

Indexed as

bevacizumabdiabetes mellitusintravitreal injectionsmacular edemaoff-label use

Identifiers

PMID33506177
PMCPMC7812399
OpenAlexW3118724712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.