Evidence map›Paper›PMID 33506077›Full record

ArticleBone reports2021

Imaging technologies in the differential diagnosis and follow-up of brown tumor in primary hyperparathyroidism: Case report and review of the literature.

Davide Diacinti, Cristiana Cipriani, Federica Biamonte, Jessica Pepe, Luciano Colangelo, Endi Kripa, Antonio Iannacone, Martina Orlandi, Vito Guarnieri, Daniele Diacinti and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Bone reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Brown tumor in the pterygopalatine fossa with maxillary and sphenoidal involvement: a rare case report and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Jaw Tumor Conundrum.Indian journal of endocrinology and metabolism
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Davide DiacintiDepartment of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Italy.
Cristiana CiprianiDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.
Federica BiamonteDepartment of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Italy.
Jessica PepeDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.
Luciano ColangeloDepartment of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Italy.
Endi KripaDepartment of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.
Antonio IannaconeDepartment of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.
Martina OrlandiDepartment of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.
Vito GuarnieriDivision of Medical Genetics, Fondazione IRCCS Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Daniele DiacintiDepartment of Radiological Sciences, Oncology and Anatomy-Pathology, Sapienza University of Rome, Italy.
Salvatore MinisolaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Italy.
Sapienza University of Rome · ITCasa Sollievo della Sofferenza · ITPoliclinico Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brown tumors are osteolytic lesions associated with hyperparathyroidism (HPT). They may involve various skeletal segments, but rarely the cranio-facial bones. We report a case of a young boy with a swelling of the jaw secondary to a brown tumor presenting as the first manifestation of primary HPT (PHPT). He was found to have brown tumor located in the skull, as well. Different imaging technologies were employed for the diagnosis and follow-up after parathyroidectomy. We enclose a review of the literature on the employment of such imaging technologies in the differential diagnosis of osteolytic lesions. A multidisciplinary approach comprising clinical, laboratory and imaging findings is essential for the differential diagnosis of brown tumor in PHPT.

Indexed as

Brown tumorMRIParathyroid adenomaPrimary hyperparathyroidism

Identifiers

PMID33506077
PMCPMC7815655
OpenAlexW3116469985

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.