ArticlePediatric gastroenterology, hepatology & nutrition2021
Diagnosis and Management of Ménétrier Disease in Children: A Case Series Review.
Article in Pediatric gastroenterology, hepatology & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Menetrier's: A pediatric chronic state of disease with a possible heritable form.JPGN reports · 2026Article
- Ménétrier disease: A clinical review.World journal of gastroenterology · 2025Review
- Unusual Suspect: Ménétrier Disease Presents as Gastric Outlet Obstruction in a Toddler.ACG case reports journal · 2025Article
- Role of gastric ultrasound in pediatric Menetrier's disease: Report of two cases.JPGN reports · 2024Article
- Clinical and Radiological Features of Menetrier's Disease: A Case Report and Review of the Literature.Cureus · 2023Article
- Chronic Ménétrier disease leading to gastric cancer in youth.Clinical endoscopy · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMénétrier disease (MD) was first described in 1888, and 50 cases have been reported until now. We aimed to discuss the etiology, diagnostics, and management of MD in children.
methodsWe searched for case reports published from 2014 till 2019 in English using PubMed. Articles were selected using subject headings and key words of interest to the topic. Interesting references of the included articles were also included.
resultsThe pathophysiology of MD is still uncertain. However, overexpression of transforming growth factor alpha with transformation of the gastric mucosa has been observed, which may be mediated by genetics and provoked by an infectious trigger. Clinically, MD is diagnosed by abdominal pain, vomiting, anorexia, and edema secondary to hypoalbuminemia. A gastroscopy with biopsy is the gold standard for the diagnosis of MD. In children, the disease is self-limiting and only requires supportive treatment. In general, children have a good prognosis and recover spontaneously within a few weeks.
conclusionFew pediatric cases of MD have been described in recent years, and with all different etiology. Endoscopy with biopsy remains the golden standard for the diagnosis of MD, and in children, the disease is self-limiting.
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