Evidence map›Paper›PMID 33505730›Full record

ArticleCase reports in critical care2021

Pneumothorax in Mechanically Ventilated Patients with COVID-19 Infection.

Raziye Ecem Akdogan, Turab Mohammed, Asma Syeda, Nasheena Jiwa, Omar Ibrahim, Rahul Mutneja

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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  15. Pneumothorax due to COVID-19: Analysis of case reports.Respiratory medicine case reports · 2021
    Article
  16. Cystic Lung Disease as a Sequela of Severe COVID-19: Case Series.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Raziye Ecem AkdoganDepartment of Internal Medicine, University of Connecticut, Farmington, Connecticut, USA.
Turab MohammedDepartment of Internal Medicine, University of Connecticut, Farmington, Connecticut, USA.ORCID https://orcid.org/0000-0001-5063-6419
Asma SyedaDepartment of Internal Medicine, University of Connecticut, Farmington, Connecticut, USA.
Nasheena JiwaDepartment of Pulmonary and Critical Care Medicine, University of Connecticut, Farmington, Connecticut, USA.
Omar IbrahimDepartment of Pulmonary and Critical Care Medicine, University of Connecticut, Farmington, Connecticut, USA.
Rahul MutnejaDepartment of Pulmonary and Critical Care Medicine, Saint Francis Hospital and Medical Center, Hartford, Connecticut, USA.ORCID https://orcid.org/0000-0001-5789-5886
University of Connecticut · USSaint Francis University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on patient-related factors associated with pneumothorax among critically ill patients with COVID-19 pneumonia is limited. Reports of spontaneous pneumothorax in patients with coronavirus disease 2019 (COVID-19) suggest that the COVID-19 infection could itself cause pneumothorax in addition to the ventilator-induced trauma among mechanically ventilated patients. Here, we report a case series of five mechanically ventilated patients with COVID-19 infection who developed pneumothorax. Consecutive cases of intubated patients in the intensive care unit with the diagnosis of COVID-19 pneumonia and pneumothorax were included. Data on their demographics, preexisting risk factors, laboratory workup, imaging findings, treatment, and survival were collected retrospectively between March and July 2020. Four out of five patients (4/5; 80%) had a bilateral pneumothorax, while one had a unilateral pneumothorax. Of the four patients with bilateral pneumothorax, three (3/4; 75%) had secondary bacterial pneumonia, two had pneumomediastinum and massive subcutaneous emphysema, and one of these two had an additional pneumoperitoneum. A surgical chest tube or pigtail catheter was placed for the management of pneumothorax. Three out of five patients with pneumothorax died (3/5; 60%), and all of them had bilateral involvement. The data from these cases suggest that pneumothorax is a potentially fatal complication of COVID-19 infection. Large prospective studies are needed to study the incidence of pneumothorax and its sequelae in patients with COVID-19 infection.

Identifiers

PMID33505730
PMCPMC7798182
OpenAlexW3118385887

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.