Evidence map›Paper›PMID 33505435›Full record

ArticleFrontiers in genetics2020

Deregulation of a

Greg L Stewart, Adam P Sage, Katey S S Enfield, Erin A Marshall, David E Cohn, Wan L Lam

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Integration analysis ofBiochemistry and biophysics reports · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Antioxidant stress and anticancer activity of peptide‑chelated seleniumInternational journal of molecular medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Greg L StewartDepartment of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.
Adam P SageDepartment of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.
Katey S S EnfieldDepartment of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.
Erin A MarshallDepartment of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.
David E CohnDepartment of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.
Wan L LamDepartment of Integrative Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong non-coding RNAs (lncRNAs) have long been implicated in cancer-associated phenotypes. Recently, a class of lncRNAs, known as

methodsLncRNA expression was determined from RNA-sequencing data of tumor and matched non-malignant tissues from 36 LUAD patients. Transcripts with significantly deregulated expression were identified and validated in a secondary LUAD RNA-seq dataset (TCGA). SiRNA-mediated knockdown of a candidate

resultsWe identified the lncRNA RP11.513I15.6, which we refer to as HMGA1-

conclusionOur results suggest that HMGA1-

Indexed as

cis-actinggene regulationHMGA1long non-coding RNAlung cancer LncRNA-Mediated Control of HMGA1 Expressionnon-coding RNA

Identifiers

PMID33505435
PMCPMC7831742
OpenAlexW3120020090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.