Evidence map›Paper›PMID 33505395›Full record

ArticleFrontiers in immunology2020

A Reproducible and Scalable Process for Manufacturing a Pfs48/45 Based

Susheel K Singh, Jordan Plieskatt, Bishwanath K Chourasia, Amanda Fabra-García, Asier Garcia-Senosiain, Vandana Singh, Karin Lövgren Bengtsson, Jenny M Reimer, Robert Sauerwein, Matthijs M Jore and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
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  9. Cloning and Recombinant Protein Expression in Lactococcus lactis.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. Article
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  15. Frontiers in cellular and infection microbiology · 2022
    Review
  16. Article
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  18. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Susheel K SinghDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Jordan PlieskattPATH's Malaria Vaccine Initiative, Washington, DC, United States.
Bishwanath K ChourasiaDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Amanda Fabra-GarcíaDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Asier Garcia-SenosiainDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Vandana SinghDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
Karin Lövgren BengtssonNovavax AB, Uppsala, Sweden.
Jenny M ReimerNovavax AB, Uppsala, Sweden.
Robert SauerweinDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Matthijs M JoreDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Michael TheisenDepartment for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.
University of Copenhagen · DKRadboud University Medical Center · NLNovavax (Sweden) · SEStatens Serum Institut · DKU.S. President's Malaria Initiative · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cysteine-rich Pfs48/45 protein, a

Indexed as

BiotechnologyIndustrial MicrobiologyAdjuvants, ImmunologicAnimalsAntibodies, ProtozoanDrug CompoundingImmunizationImmunogenicity, VaccineLactobacillusMalaria, FalciparumMalaria VaccinesMembrane GlycoproteinsMiceNanoparticlesProtein ConformationProtein FoldingAdjuvants, ImmunologicAntibodies, ProtozoanMalaria VaccinesMatrix-MMembrane Glycoproteinspfs48-45 protein, Plasmodium falciparumProtozoan ProteinsSaponinsVaccines, Syntheticcurrent Good Manufacturing PracticesLactococcus lactismalariaPfs48/45R0.6Ctransmission-blockingvaccine

Identifiers

PMID33505395
PMCPMC7832176
OpenAlexW3121086034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.