Evidence map›Paper›PMID 33505345›Full record

ArticleFrontiers in neurology2020

Case Report: Novel Arylsulfatase A (

Lulu Xu, Meixiang Zhong, Yajuan Wang, Zhihong Wang, Jie Song, Jing Zhao, Hongyun Yu, Zhencui Yang, Wenjing Yan, Xueping Zheng

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Lulu XuDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Meixiang ZhongDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yajuan WangDepartment of Geriatric Medicine, The Qingdao Eighth People's Hospital, Qingdao, China.
Zhihong WangDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jie SongDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jing ZhaoDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hongyun YuDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhencui YangDepartment of Clinical Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.
Wenjing YanDepartment of Neurology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xueping ZhengDepartment of Geriatric Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China.
Affiliated Hospital of Qingdao University · CNQingdao University · CNQingdao Eighth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metachromatic leukodystrophy (MLD) is an autosomal recessive hereditary disorder characterized by the accumulation of sulfatide in the central and peripheral nervous systems. Herein, we present the case of an adult patient with MLD who had mild cognitive and psychiatric dysfunctions and severe vision disturbance, who was initially misdiagnosed as multiple sclerosis. Through genetic screening, this patient was later identified to have a full deletion of exon 4 and the novel p.P220L mutation in the arylsulfatase A (

Indexed as

adult onsetarylsulphatase Adeletion mutationmetachromatic leukodystrophyvisual dysfunction

Identifiers

PMID33505345
PMCPMC7830158
OpenAlexW3118661072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.