Evidence map›Paper›PMID 33505144›Full record

ArticleWorld journal of gastroenterology2020

Oral microbiome and pancreatic cancer.

Ai-Lin Wei, Mao Li, Guo-Qing Li, Xuan Wang, Wei-Ming Hu, Zhen-Lu Li, Jue Yuan, Hong-Ying Liu, Li-Li Zhou, Ka Li and 2 more

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Oral and Pancreatobiliary Microbiota in Cancer: A Systematic Review of Compositional Alterations and Their Clinical Implications.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026
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  14. Challenges of early detection of pancreatic cancer.The Journal of clinical investigation · 2025
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ai-Lin WeiDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Mao LiDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Guo-Qing LiWest China School of Public Health/West China fourth Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Xuan WangWest China School of Public Health/West China fourth Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Wei-Ming HuDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Zhen-Lu LiDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Jue YuanDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Hong-Ying LiuDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Li-Li ZhouDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China.
Ka LiWest China Hospital/West China School of Nursing, Sichuan University, Chengdu 610000, Sichuan Province, China.
Ang LiDepartment of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China. angli@scu.edu.cn.
Mei Rosemary FuBoston College William F. Connell School of Nursing, Boston College William F. Connell School, MA, 02467, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobiota profiles differ between patients with pancreatic cancer and healthy people, and understanding these differences may help in early detection of pancreatic cancer. Saliva sampling is an easy and cost-effective way to determine microbiota profiles compared to fecal and tissue sample collection.

aimTo investigate the saliva microbiome distribution in patients with pancreatic adenocarcinoma (PDAC) and the role of oral microbiota profiles in detection and risk prediction of pancreatic cancer.

methodsWe conducted a prospective study of patients with pancreatic cancer (

resultsCompared with the healthy control group, carriage of

conclusionSaliva microbiome was able to distinguish patients with pancreatic cancer and healthy individuals.

Indexed as

AdenocarcinomaMicrobiotaPancreatic NeoplasmsChinaHumansProspective StudiesRNA, Ribosomal, 16SSalivaRNA, Ribosomal, 16S16s rRNACancer detectionDysbiosisHigh-throughput sequencingOral microbiotaPancreatic cancer

Identifiers

PMID33505144
PMCPMC7789059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.