ArticleNature2021
Systematic analysis of binding of transcription factors to noncoding variants.
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Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.
0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
26.3field-weighted citation impact, top 1% of its field
What it found
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Who cites it
100 citing papers in PubMed, 171 citations in OpenAlex.
- Association of Bilateral Vestibulopathy With theNeurology. Genetics · 2026Article
- Mechanisms underlying disease-causing variants in promoters and enhancers.Nature genetics · 2026Review
- Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants.Nature communications · 2026Article
- FABIAN-variant 2026: improved prediction of the effects of DNA variants on transcription factor binding.Nucleic acids research · 2026Article
- SELEX-Based Aptamer Technologies for Toxin Analysis: Screening, Optimization, and Computational Assisted Design.Toxins · 2026Review
- ASAP1 gene InDel variants are associated with enhanced goat resistance against Brucella infection.Animal bioscience · 2026Article
- Decoding common and rare noncoding variant effects across cellular and developmental contexts.Nature genetics · 2026Article
- Autoimmune non-coding variants perturb transcription factor-cofactor complex assembly linked to enhancer activity.bioRxiv : the preprint server for biology · 2026Article
- Genetic association and machine learning improve the prediction of type 1 diabetes risk.Nature genetics · 2026Article
- Kilobase-scale compartments enabled by CRUSH reveal regulatory programs across cell types, single-cells, and ancient mammoths.bioRxiv : the preprint server for biology · 2026Article
- Differential chromatin looping regulated by two GA-binding transcription factors creates an X-specific chromatin environment for dosage compensation.bioRxiv : the preprint server for biology · 2026Article
- Systematic analysis of functional genetic and epigenetic variants in colorectal cancer.Science advances · 2026Article
- A functional ancestry-linked regulatory haplotype influences CYP2D6 expression.The pharmacogenomics journal · 2026Article
- Glycerol 3-phosphate acyltransferase exacerbates α-synuclein-induced toxicity by increasing lipid peroxidation.Nature communications · 2026Article
- Mixed-model and transcriptome-wide association analyses identify transcription factors and genes associated with colorectal cancer susceptibility.Nature communications · 2026Article
- baal-nf identifies motif-disrupting variants that decrease transcription factor binding affinity.Genome biology · 2026Article
- Global Evaluation of Congenital Heart Disease-Associated Non-Coding Variants.Research square · 2026Article
- The IGVF catalog-from genetic variation to function.Nucleic acids research · 2026Article
- A structure-guided approach to noncoding variant evaluation for transcription factor binding using AlphaFold 3.Nucleic acids research · 2026Article
- iHalo: a genome-based machine learning model using k-mer for halophiles identification.World journal of microbiology & biotechnology · 2025Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 7 institutions in 8 countries.
Jian Yan *School of Medicine, Northwest University, Xi'an, China. jian.yan@cityu.edu.hk.ORCID http://orcid.org/0000-0002-1267-2870
Yunjiang Qiu *Ludwig Institute for Cancer Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-0539-9714
André M Ribeiro Dos Santos *Ludwig Institute for Cancer Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-7005-3576
Yimeng YinDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden.ORCID http://orcid.org/0000-0002-5454-608X
Yang E LiLudwig Institute for Cancer Research, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6997-6018
Nick VinckierDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Naoki NariaiDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Paola BenaglioDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Anugraha RamanLudwig Institute for Cancer Research, La Jolla, CA, USA.
Xiaoyu LiSchool of Medicine, Northwest University, Xi'an, China.
Shicai FanDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Joshua ChiouDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-4618-0647
Fulin ChenSchool of Medicine, Northwest University, Xi'an, China.
Kelly A FrazerDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-6060-8902
Kyle J GaultonDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Maike SanderDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5308-7785
Jussi TaipaleDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, Solna, Sweden. ajt208@cam.ac.uk.ORCID http://orcid.org/0000-0003-4204-0951
Bing RenLudwig Institute for Cancer Research, La Jolla, CA, USA. biren@ucsd.edu.ORCID http://orcid.org/0000-0002-5435-1127
University of California San Diego · USCity University of Hong Kong · HKLudwig Cancer Research · USLudwig Cancer Research · BENorthwest University · CNUniversity of Cambridge · GBUniversity of Helsinki · FI
Funding
The impact of genomic variation on environment-induced changes in pancreatic beta cell statesU01HG012059 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Hannah Kathryn Carter, Kyle Jeffrie Gaulton · 2021 to 2026
$7.5MPredoctoral and Postdoctoral Training in Cancer Cell BiologyT32CA067754 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEAN Y.J. WANG · 1995 to 2026
$6.5MFunctional Analysis of T2D Associated Non-coding SNPsU01DK105541 · NIDDK · LUDWIG INSTITUTE FOR CANCER RES LTD · PI FRAZER, KELLY A, REN, BING · 2015 to 2019
$4.6MMedical Research Council MR/V000500/1NCI NIH HHS T32 CA067754NHGRI NIH HHS U01 HG012059NIDDK NIH HHS U01 DK105541
Abstract
Many sequence variants have been linked to complex human traits and diseases
Indexed as
SELEX Aptamer TechniqueSupport Vector MachineBinding SitesDiseaseGenome, HumanHumansLigandsPolymorphism, Single NucleotideProtein BindingTranscription FactorsLigandsTranscription Factors
Identifiers
What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.