Evidence map›Paper›PMID 33505020›Full record

ArticleNature2021

Ebola virus antibody decay-stimulation in a high proportion of survivors.

Charlene Adaken, Janet T Scott, Raman Sharma, Robin Gopal, Steven Dicks, Saidia Niazi, Samreen Ijaz, Tansy Edwards, Catherine C Smith, Christine P Cole and 13 more

Open access · bronzeAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  15. Post-Ebola Symptoms 7 Years After Infection: The Natural History of Long Ebola.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  16. Pseudotyped Viruses for Marburgvirus and Ebolavirus.Advances in experimental medicine and biology · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 19 institutions in 6 countries.

Charlene Adaken *Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary & Ecological Sciences, University of Liverpool, Liverpool, UK.
Janet T Scott *NIHR Health Protection Research Unit in Emerging and Zoonotic Infections (HPRU EZI), University of Liverpool, Liverpool, UK.
Raman Sharma *Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, UK.
Robin GopalHigh Containment Microbiology, National Infections Service, Public Health England, London, UK.
Steven DicksBlood Borne Virus Unit, National Infection Service, Public Health England, London, UK.ORCID http://orcid.org/0000-0002-4709-9664
Saidia NiaziBlood Borne Virus Unit, National Infection Service, Public Health England, London, UK.
Samreen IjazBlood Borne Virus Unit, National Infection Service, Public Health England, London, UK.
Tansy EdwardsMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Catherine C SmithFaculty of Health and Life Science, University of Liverpool, Liverpool, UK.
Christine P ColeCollege of Medicine and Allied Health Sciences, Freetown, Sierra Leone.
Philip KamaraNational Safe Blood Service, Ministry of Health and Sanitation, Freetown, Sierra Leone.
Osman KargboNational Safe Blood Service, Ministry of Health and Sanitation, Freetown, Sierra Leone.
Heidi A DoughtyNational Health Service Blood and Transplant, Birmingham, UK.
Johan van GriensvenInstitute of Tropical Medicine, Antwerp, Belgium.
Peter W HorbyCentre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Sahr M GevaoNational Safe Blood Service, Ministry of Health and Sanitation, Freetown, Sierra Leone.
Foday SahrCollege of Medicine and Allied Health Sciences, University of Sierra Leone, Freetown, Sierra Leone.
Ebola-CP Consortium
Richard J DimelowGlaxoSmithKline, Stevenage, UK.
Richard S TedderNIHR Health Protection Research Unit in Emerging and Zoonotic Infections (HPRU EZI), University of Liverpool, Liverpool, UK.
Malcolm G SempleNIHR Health Protection Research Unit in Emerging and Zoonotic Infections (HPRU EZI), University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0001-9700-0418
William A PaxtonDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary & Ecological Sciences, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0001-5200-0801
Georgios PollakisDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary & Ecological Sciences, University of Liverpool, Liverpool, UK. g.pollakis@liverpool.ac.uk.ORCID http://orcid.org/0000-0002-9659-5461
University of Liverpool · GBUniversity of Sierra Leone · SLNational Health Service · GBInstituut voor Tropische Geneeskunde · BEMinistry of Health and Sanitation · SLLondon School of Hygiene & Tropical Medicine · GBPublic Health England · GBUniversity of Oxford · GBKing's College London · GBUniversity of North Carolina at Chapel Hill · USWorld Health Organization · CHBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEClinical Research Management · USDuke University · USGlaxoSmithKline (United Kingdom) · GBLiverpool School of Tropical Medicine · GBRoslin Institute · GBSierra Leone Urban Research Centre · SLUniversity of Exeter · GB

Funding

Medical Research Council MC_UU_12014/8Medical Research Council MR/R010161/1Wellcome TrustWellcome Trust 106491
6 · The paper itself

Abstract

Neutralizing antibody function provides a foundation for the efficacy of vaccines and therapies

Indexed as

ConvalescenceSurvivorsAdolescentAdultAfrica, WesternAntibodies, NeutralizingAntibodies, ViralCohort StudiesEbolavirusFemaleHalf-LifeHemorrhagic Fever, EbolaHumansMaleMiddle AgedNeutralization TestsAntibodies, NeutralizingAntibodies, Viral

Identifiers

PMID33505020
PMCPMC7839293
OpenAlexW3123601689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.