Evidence map›Paper›PMID 33504947›Full record

ArticleScientific reports2021

Comparison of the surgical outcomes of free flap reconstruction for primary and recurrent head and neck cancers: a case-controlled propensity score-matched study of 1,791 free flap reconstructions.

Kuan-Hua Chen, Spencer C H Kuo, Peng-Chen Chien, Hsiao-Yun Hsieh, Ching-Hua Hsieh

Abstract readCase Reports
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kuan-Hua ChenDepartment of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University and College of Medicine, No. 123, Ta-Pei Road, Niao-Song District, Kaohsiung City, 83301, Taiwan.
Spencer C H KuoDepartment of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University and College of Medicine, No. 123, Ta-Pei Road, Niao-Song District, Kaohsiung City, 83301, Taiwan.
Peng-Chen ChienDepartment of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University and College of Medicine, No. 123, Ta-Pei Road, Niao-Song District, Kaohsiung City, 83301, Taiwan.
Hsiao-Yun HsiehDepartment of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University and College of Medicine, No. 123, Ta-Pei Road, Niao-Song District, Kaohsiung City, 83301, Taiwan.
Ching-Hua HsiehDepartment of Plastic Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University and College of Medicine, No. 123, Ta-Pei Road, Niao-Song District, Kaohsiung City, 83301, Taiwan. m93chinghua@gmail.com.

Funding

Chang Gung Memorial Hospital CDRPG8H0013
6 · The paper itself

Abstract

This study was designed to compare the outcome and analyze the operation-related risk factors in free flap reconstruction for patients with primary and recurrent head and neck cancers. A 1:1 propensity score-matched analysis of the microsurgery registry database of the hospital. The primary outcome of the free flap reconstruction had a higher failure rate in the recurrent group than the primary group (5.1% vs. 3.1%, p = 0.037). Among the 345 pairs in the matched study population, there were no significant differences between the primary and recurrent groups regarding the rate of total flap loss (3.5% vs. 5.5%, p = 0.27) and secondary outcomes. This study revealed that free flap reconstruction had a higher failure rate in the recurrent group than the primary group, but such a difference may be attributed by the different patient characteristics.

Indexed as

Free Tissue FlapsFemaleHead and Neck NeoplasmsHumansMaleMicrosurgeryMiddle AgedNeoplasm Recurrence, LocalPlastic Surgery ProceduresPropensity ScoreRetrospective StudiesTreatment Outcome

Identifiers

PMID33504947
PMCPMC7840944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.