Evidence map›Paper›PMID 33504791›Full record

ArticleNature communications2021

Ancient proteins provide evidence of dairy consumption in eastern Africa.

Madeleine Bleasdale, Kristine K Richter, Anneke Janzen, Samantha Brown, Ashley Scott, Jana Zech, Shevan Wilkin, Ke Wang, Stephan Schiffels, Jocelyne Desideri and 18 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Bone health: biology and nutrition.Current opinion in clinical nutrition and metabolic care · 2024
    Pooled it
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  5. Review
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  11. Article
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  13. Saturated fat in an evolutionary context.Lipids in health and disease · 2025
    Review
  14. Article
  15. Nutrition and Osteoporosis Prevention.Current osteoporosis reports · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 8 institutions in 10 countries.

Madeleine BleasdaleDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany. bleasdale@shh.mpg.de.ORCID 0000-0002-8021-0862
Kristine K RichterDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.
Anneke JanzenDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.
Samantha BrownDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0001-5001-525X
Ashley ScottDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0001-8892-1557
Jana ZechDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.
Shevan WilkinDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0003-0797-6244
Ke WangDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0003-3935-8344
Stephan SchiffelsDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0002-1017-9150
Jocelyne DesideriLaboratory of Prehistoric Archaeology and Anthropology, Department F.-A. Forel for Environmental and Aquatic Sciences, Université de Genève, Geneva, Switzerland.ORCID 0000-0003-1372-7420
Marie BesseLaboratory of Prehistoric Archaeology and Anthropology, Department F.-A. Forel for Environmental and Aquatic Sciences, Université de Genève, Geneva, Switzerland.ORCID 0000-0002-4752-9070
Jacques ReinoldSection française de la Direction des antiquités du Soudan, Khartoum, Sudan.
Mohamed SaadNational Corporation for Antiquities and Museums of Sudan, M.Bolheim Bioarchaeology Laboratory, Khartoum, Sudan.
Hiba BabikerDepartment of Linguistic and Cultural Evolution, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0001-7947-285X
Robert C PowerDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0001-7425-5709
Emmanuel NdiemaDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.
Christine OgolaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.
Fredrick K ManthiDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.
Muhammad ZahirDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0002-1765-6319
Michael PetragliaDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0003-2522-5727
Christian TrachselFunctional Genomics Center, University of Zurich/ETH, Zurich, Switzerland.
Paolo NanniFunctional Genomics Center, University of Zurich/ETH, Zurich, Switzerland.ORCID 0000-0001-8429-3557
Jonas GrossmannFunctional Genomics Center, University of Zurich/ETH, Zurich, Switzerland.ORCID 0000-0002-6899-9020
Jessica HendyDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0002-3718-1058
Alison CrowtherDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.
Patrick RobertsDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0002-4403-7548
Steven T GoldsteinDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany.ORCID 0000-0001-6703-7033
Nicole BoivinDepartment of Archaeology, Max Planck Institute for the Science of Human History, Jena, Germany. boivin@shh.mpg.de.ORCID 0000-0002-7783-4199
Max Planck Institute for the Science of Human History · DENational Museums of Kenya · KEUniversity of Zurich · CHNational Museum of Natural History · USThe University of Queensland · AUUniversity of Geneva · CHHazara University · PKNational Centre for Research · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consuming the milk of other species is a unique adaptation of Homo sapiens, with implications for health, birth spacing and evolution. Key questions nonetheless remain regarding the origins of dairying and its relationship to the genetically-determined ability to drink milk into adulthood through lactase persistence (LP). As a major centre of LP diversity, Africa is of significant interest to the evolution of dairying. Here we report proteomic evidence for milk consumption in ancient Africa. Using liquid chromatography tandem mass spectrometry (LC-MS/MS) we identify dairy proteins in human dental calculus from northeastern Africa, directly demonstrating milk consumption at least six millennia ago. Our findings indicate that pastoralist groups were drinking milk as soon as herding spread into eastern Africa, at a time when the genetic adaptation for milk digestion was absent or rare. Our study links LP status in specific ancient individuals with direct evidence for their consumption of dairy products.

Indexed as

DairyingFeeding BehaviorAfrica, EasternAmino Acid SequenceAnimalsArchaeologyBone and BonesCattleCollagenDental CalculusGeographyHumansIsotope LabelingLactaseLactoglobulinsMilk ProteinsCollagenLactaseLactoglobulinsMilk Proteins

Identifiers

PMID33504791
PMCPMC7841170
OpenAlexW3123079134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.