Evidence map›Paper›PMID 33504761›Full record

ArticleSignal transduction and targeted therapy2021

Hepatic microRNA-126 deficiency restrains liver regeneration through p53 pathway in mice.

Lingling Zhang, Yugang Qiu, Fan Yang, Jiyuan Yao, Ying Wang, Yang Qin, Hanchuan Mou, Qing Jing, Leiming Liu, Zhenyu Ju

Abstract readLetter
In one paragraph

Article in Signal transduction and targeted therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lingling Zhang *Key Laboratory of Aging and Cancer Biology of Zhejiang Province, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China.
Yugang Qiu *School of Rehabilitation Medicine, Weifang Medical University, Weifang, China.
Fan Yang *School of Public Health and Management, Weifang Medical University, Weifang, China.
Jiyuan YaoKey Laboratory of Aging and Cancer Biology of Zhejiang Province, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China.
Ying WangKey Laboratory of Aging and Cancer Biology of Zhejiang Province, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China.
Yang QinKey Laboratory of Aging and Cancer Biology of Zhejiang Province, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China.
Hanchuan MouKey Laboratory of Regenerative Medicine of Ministry of Education, Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China.
Qing JingCAS Key Lab of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China. jing@sibs.ac.cn.
Leiming LiuKey Laboratory of Regenerative Medicine of Ministry of Education, Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine, Jinan University, Guangzhou, China. liuleiming77@163.com.
Zhenyu JuKey Laboratory of Aging and Cancer Biology of Zhejiang Province, Institute of Aging Research, School of Medicine, Hangzhou Normal University, Hangzhou, China. zhenyuju@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsGene Expression Regulation, DevelopmentalHepatocytesHumansLiverLiver RegenerationMiceMice, KnockoutMicroRNAsTumor Suppressor Protein p53MicroRNAsMIRN126 microRNA, mouseTrp53 protein, mouseTumor Suppressor Protein p53

Identifiers

PMID33504761
PMCPMC7841169

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.