Evidence map›Paper›PMID 33504591›Full record

ArticleJournal of clinical microbiology2021

Recognition of Diagnostic Gaps for Laboratory Diagnosis of Fungal Diseases: Expert Opinion from the Fungal Diagnostics Laboratories Consortium (FDLC).

Sean X Zhang, N Esther Babady, Kimberly E Hanson, Amanda T Harrington, Paige M K Larkin, Sixto M Leal, Paul M Luethy, Isabella W Martin, Preeti Pancholi, Gary W Procop and 6 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Review of the Microbial Spectrum of Mixed Respiratory Fungal Infections.Journal of epidemiology and global health · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Optimizing filamentous fungi identification by MALDI-TOF MS: A comparative analysis of key factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  8. Article
  9. Review
  10. Masquerading Yeast: A Case Report ofOpen forum infectious diseases · 2025
    Article
  11. Review
  12. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  13. An overview of the laboratory diagnosis ofJournal of clinical microbiology · 2025
    Review
  14. Article
  15. Review
  16. Evaluation of a New Automated Mono-Test for the Detection ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  17. Review
  18. Cavitary lung lesions caused byBMJ case reports · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 15 institutions in 1 country.

Sean X ZhangDivision of Medical Microbiology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
N Esther BabadyClinical Microbiology Service and Infectious Disease Service, Departments of Laboratory Medicine and Medicine, Memorial Sloan Kettering Cancer Center, New York City, New York, USA.
Kimberly E HansonDepartment of Pathology, Section of Clinical Microbiology, University of Utah and ARUP Laboratories, Salt Lake City, Utah, USA.
Amanda T HarringtonDepartment of Pathology and Laboratory Medicine, Loyola University Medical Center, Maywood, Illinois, USA.
Paige M K LarkinDepartment of Pathology and Laboratory Medicine, NorthShore University HealthSystem, Evanston, Illinois, USA.
Sixto M LealDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Paul M LuethyDepartment of Pathology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Isabella W MartinDepartment of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Preeti PancholiDepartment of Pathology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Gary W ProcopPathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Stefan RiedelClinical Microbiology Laboratories, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Seyedmojtaba SeyedmousaviMicrobiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Kaede V SullivanDepartment of Pathology and Laboratory Medicine, Lewis Katz School of Medicine at Temple University, Temple University Health System, Philadelphia, Pennsylvania, USA.
Thomas J WalshDivision of Infectious Diseases, Weill Cornell Medicine of Cornell University, New York-Presbyterian Hospital, New York City, New York, USA.
Shawn R LockhartMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Fungal Diagnostics Laboratories Consortium (FDLC)
Beth Israel Deaconess Medical Center · USCenters for Disease Control and Prevention · USCleveland Clinic · USDartmouth–Hitchcock Medical Center · USJohns Hopkins University · USLoyola University Medical Center · USMemorial Sloan Kettering Cancer Center · USNational Institutes of Health Clinical Center · USNewYork–Presbyterian Hospital · USNorthShore University HealthSystem · USThe Ohio State University Wexner Medical Center · USUniversity Health System · USUniversity of Alabama at Birmingham · USUniversity of Maryland, Baltimore · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal infections are a rising threat to our immunocompromised patient population, as well as other nonimmunocompromised patients with various medical conditions. However, little progress has been made in the past decade to improve fungal diagnostics. To jointly address this diagnostic challenge, the Fungal Diagnostics Laboratory Consortium (FDLC) was recently created. The FDLC consists of 26 laboratories from the United States and Canada that routinely provide fungal diagnostic services for patient care. A survey of fungal diagnostic capacity among the 26 members of the FDLC was recently completed, identifying the following diagnostic gaps: lack of molecular detection of mucormycosis; lack of an optimal diagnostic algorithm incorporating fungal biomarkers and molecular tools for early and accurate diagnosis of

Indexed as

LaboratoriesMucoralesCanadaClinical Laboratory TechniquesHumans

Identifiers

PMID33504591
PMCPMC8218742
OpenAlexW3125504512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.