Evidence map›Paper›PMID 33504178›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Conventional and Novel Lipid Measures and Risk of Peripheral Artery Disease.

Minghao Kou, Ning Ding, Shoshana H Ballew, Maya J Salameh, Seth S Martin, Elizabeth Selvin, Gerardo Heiss, Christie M Ballantyne, Kunihiro Matsushita, Ron C Hoogeveen

Open access · bronzeAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Minghao KouDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (M.K., N.D., S.H.B., S.S.M., E.S., K.M.).
Ning DingDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (M.K., N.D., S.H.B., S.S.M., E.S., K.M.).
Shoshana H BallewDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (M.K., N.D., S.H.B., S.S.M., E.S., K.M.).
Maya J SalamehDivision of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD (M.J.S., S.S.M., K.M.).
Seth S MartinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (M.K., N.D., S.H.B., S.S.M., E.S., K.M.).
Elizabeth SelvinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (M.K., N.D., S.H.B., S.S.M., E.S., K.M.).
Gerardo HeissDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC (G.H.).
Christie M BallantyneDepartment of Medicine, Baylor College of Medicine, Houston, TX (C.M.B., R.C.H.).
Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (M.K., N.D., S.H.B., S.S.M., E.S., K.M.).
Ron C HoogeveenDepartment of Medicine, Baylor College of Medicine, Houston, TX (C.M.B., R.C.H.).
Johns Hopkins University · USBaylor College of Medicine · USUniversity of North Carolina at Chapel Hill · US

Funding

Sex Hormones in Pulmonary Arterial HypertensionP01HL108800 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NEWMAN, JOHN HUGHES · 2012 to 2021
$22.0M
Profiling Cardiovascular Events and Biomarkers in the Very Old to Improve Personalized Approaches for the Prevention of Cardiac and Vascular DiseaseR01HL134320 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI BALLANTYNE, CHRISTIE MITCHELL, SELVIN, ELIZABETH · 2016 to 2019
$3.1M
National Trend and Predictors of Critical Limb Ischemia HospitalizationsR21HL133694 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI MATSUSHITA, KUNIHIRO · 2016 to 2017
$245k
NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS P01 HL108800NHLBI NIH HHS R01 HL134320NHLBI NIH HHS R21 HL133694
6 · The paper itself

Abstract

objectiveThe aim of this study was to comprehensively assess the association of multiple lipid measures with incident peripheral artery disease (PAD). Approach and Results: We used Cox proportional hazards models to characterize the associations of each of the fasting lipid measures (total cholesterol, LDL-C [low-density lipoprotein cholesterol], HDL-C [high-density lipoprotein cholesterol], triglycerides, RLP-C [remnant lipoprotein cholesterol], LDL-TG [LDL-triglycerides], sdLDL-C [small dense LDL-C], and Apo-E-HDL [Apo-E-containing HDL-C]) with incident PAD identified by pertinent

conclusionsTriglyceride-related and HDL-related lipids were independently associated with incident PAD, which has implications on preventive strategies for PAD. However, none of the novel lipid measures outperformed conventional ones. Graphic Abstract: A graphic abstract is available for this article.

Indexed as

AgedAged, 80 and overApolipoproteins ECholesterolCholesterol, HDLCholesterol, LDLCohort StudiesDyslipidemiasFemaleHumansLipidsLipoproteinsLipoproteins, HDLLipoproteins, LDLMalePeripheral Arterial Diseaseapolipoprotein E-rich HDLApolipoproteins ECholesterolCholesterol, HDLCholesterol, LDLLipidslipoprotein cholesterolLipoproteinsLipoproteins, HDLLipoproteins, LDLlow density lipoprotein triglycerideremnant-like particle cholesterolTriglyceridescholesterollipidslipoproteinsperipheral artery diseasetriglycerides

Identifiers

PMID33504178
PMCPMC8188625
OpenAlexW3122323559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.