ReviewClinical and molecular hepatology2021
Changes in the epidemiology and management of bacterial infections in cirrhosis.
Review in Clinical and molecular hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07465003 (Use of Antimicrobial Drugs in Severe Infections and Epidemiological Study of Populations With Severe Infections), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Antimicrobial Drugs in Severe Infections and Epidemiological Study of Populations With Severe Infections
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Humoral Immunogenicity to SARS-CoV-2 Vaccination in Liver Transplant Recipients: A Systematic Review and Meta-Analysis.International journal of biological sciences · 2022Pooled it
- Proteomics-based machine learning model for predicting secondary infection in HBV-related liver failure.Nature communications · 2026Article
- Interpretable model for early prediction of 28-day mortality in patients with cirrhosis and sepsis: a multi-cohort ICU study.BMC gastroenterology · 2026Article
- Clinical efficacy of empiric antibiotic therapy in Chinese patients with cirrhosis and bacterial infections: A multicenter study.PloS one · 2026Article
- Real-world evidence on predictors of antimicrobial resistance among patients with chronic liver disease.Frontiers in medicine · 2026Article
- Sepsis in end-stage liver disease and acute-on-chronic liver failure: pathophysiology, diagnostic challenges, and pharmacological management.Frontiers in pharmacology · 2026Review
- Associations of lactate-to-hematocrit ratio with short- and long-term prognoses in critically ill patients with cirrhosis and sepsis: a retrospective cohort study.BMC infectious diseases · 2025Article
- Predictive role of the Albumin-Bilirubin score in ICU patients with cirrhosis and sepsis: insights from a large retrospective cohort.BMC gastroenterology · 2025Article
- A National Survey Shows a Dilemma Toward Spontaneous Bacterial Peritonitis Prophylaxis Among US-Based Hepatology Professionals.Clinical and translational gastroenterology · 2025Article
- Prognostic Value of Inflammatory Markers in Septic Critically Ill Patients with Chronic Liver Disease: A Retrospective Analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- Infection risk and management in patients with cirrhosis: A critical overview.World journal of hepatology · 2025Article
- Bacterial resistance profile and its association with poor outcome among cirrhosis patients attending a tertiary care referral center in northern India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Observational
- Relationship between coagulopathy score and survival in critically ill patients with liver cirrhosis and sepsis: a retrospective study.BMC infectious diseases · 2025Article
- Lactate-to-albumin ratio as a potential prognostic predictor in patients with cirrhosis and sepsis: a retrospective cohort study.BMC infectious diseases · 2025Article
- Article
- Machine learning-based nomogram for mortality risk stratification in cirrhotic patients with sepsis: a single-center predictive model.Frontiers in medicine · 2025Article
- Increased serum albumin corrected anion gap levels are associated with poor prognosis in septic patients with liver cirrhosis.Scientific reports · 2024Article
- Article
- Prevalence and predictors of multidrug-resistant bacteremia in liver cirrhosis.The Korean journal of internal medicine · 2024Article
- Development of a nomogram for predicting in-hospital mortality in patients with liver cirrhosis and sepsis.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Patients with cirrhosis are susceptible to develop infections because of immune dysfunction, changes in microbiome and increase in bacterial translocation from the gut to systemic circulation. Bacterial infections can worse the clinical course of the disease, triggering the development of complications such as acute kidney injury, hepatic encephalopathy, organ failures and acute on chronic liver failure. In recent years, the spread of multi drug resistant bacteria made more challenging the management of infections in patients with cirrhosis. Hence, the mortality rate associated to sepsis is increasing in these patients. Therefore, the optimization of the management of infections has a high priority in cirrhosis. Herein we reviewed the recent changes in the epidemiology and the management of bacterial infections in patients with liver cirrhosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.