Evidence map›Paper›PMID 33504095›Full record

ArticleMolecules (Basel, Switzerland)2021

The Impact of Composites with Silicate-Based Glasses and Gold Nanoparticles on Skin Wound Regeneration.

Sorin M Mârza, Klara Magyari, Sidonia Bogdan, Mirela Moldovan, Cosmin Peștean, Andras Nagy, Adrian Florin Gal, Flaviu Tăbăran, Robert Cristian Purdoiu, Emilia Licărete and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Potential of Composite Cements for Wound Healing in Rats.Bioengineering (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Sorin M MârzaFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Klara MagyariInterdisciplinary Research Institute on Bio-Nano-Science, Babeș-Bolyai University, 400271 Cluj-Napoca, Romania.ORCID 0000-0003-1770-8454
Sidonia BogdanFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Mirela MoldovanFaculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.ORCID 0000-0003-1255-9373
Cosmin PeșteanFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Andras NagyFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Adrian Florin GalFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Flaviu TăbăranFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0001-5744-0451
Robert Cristian PurdoiuFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-6486-783X
Emilia LicăreteInterdisciplinary Research Institute on Bio-Nano-Science, Babeș-Bolyai University, 400271 Cluj-Napoca, Romania.ORCID 0000-0003-1190-6003
Sorina SuarasanInterdisciplinary Research Institute on Bio-Nano-Science, Babeș-Bolyai University, 400271 Cluj-Napoca, Romania.
Lucian BaiaFaculty of Physics, Babeș-Bolyai University, 400084 Cluj-Napoca, Romania.ORCID 0000-0003-3196-4868
Ionel PapucFaculty of Veterinary Medicine, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · ROBabeș-Bolyai University · ROIuliu Hațieganu University of Medicine and Pharmacy · ROUniversity of Szeged · HU

Funding

Ministry of Research and Innovation CNCSIS-UEFISCDI PN-III-P1.1.1-TE-2019-1138New National Excellence Program of the Ministry for Innovation and Technology UNKP-20-5-SZTE-657
6 · The paper itself

Abstract

The silver content of the skin regeneration ointments can influence its regeneration process but in the meantime, it can take the benefit of the antibacterial properties of silver by avoiding the bacterial infection of an open wound. In the current study, the skin healing and regeneration capacity of bioactive glass with spherical gold nanocages (BGAuIND) in the Vaseline ointments were evaluated in vivo comparing the bioactive glass (BG)-Vaseline and bioactive glass with spherical gold (BGAuSP)-Vaseline ointments. Spherical gold nanocages are stabilized with silver and as a consequence the BGAuIND exhibits great antibacterial activity. Histological examination of the cutaneous tissue performed on day 8 indicates a more advanced regeneration process in rats treated with BGAuSP-Vaseline. The histopathological examination also confirms the results obtained after 11 days post-intervention, when the skin is completely regenerated at rats treated with BGAuSP-Vaseline compared with the others groups where the healing was incomplete. This result is also confirmed by the macroscopic images of the evolution of wounds healing. As expected, the silver content influences the wound healing process but after two weeks, for all of the post-interventional trials from the groups of rats, the skin healing was completely.

Indexed as

AnimalsAnti-Bacterial AgentsCell LineFemaleGlassGoldHumansMetal NanoparticlesRatsRegenerationSilicatesSilverSkinWound HealingAnti-Bacterial AgentsGoldSilicatesSilverhistopathologyimmunological assayin vivoVaselinewound healing

Identifiers

PMID33504095
PMCPMC7866013
OpenAlexW3125241749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.