Evidence map›Paper›PMID 33504048›Full record

ArticleBiomolecules2021

Type III Collagen is Required for Adipogenesis and Actin Stress Fibre Formation in 3T3-L1 Preadipocytes.

Mohammad Al Hasan, Patricia E Martin, Xinhua Shu, Steven Patterson, Chris Bartholomew

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  8. bioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. MMPP promotes adipogenesis and glucose uptakeFrontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohammad Al HasanDepartment of Biological & Biomedical Sciences, School of Health & Life Sciences, City Campus, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 OBA, UK.ORCID 0000-0002-4756-7245
Patricia E MartinDepartment of Biological & Biomedical Sciences, School of Health & Life Sciences, City Campus, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 OBA, UK.ORCID 0000-0003-0890-8059
Xinhua ShuDepartment of Biological & Biomedical Sciences, School of Health & Life Sciences, City Campus, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 OBA, UK.ORCID 0000-0003-3760-3019
Steven PattersonDepartment of Biological & Biomedical Sciences, School of Health & Life Sciences, City Campus, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 OBA, UK.ORCID 0000-0003-1220-9832
Chris BartholomewDepartment of Biological & Biomedical Sciences, School of Health & Life Sciences, City Campus, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 OBA, UK.ORCID 0000-0002-1153-8389
Glasgow Caledonian University · GB

Funding

Kuwait Cultural Bureau, London, UK G1469
6 · The paper itself

Abstract

GPR56 is required for the adipogenesis of preadipocytes, and the role of one of its ligands, type III collagen (ColIII), was investigated here. ColIII expression was examined by reverse transcription quantitative polymerase chain reaction, immunoblotting and immunostaining, and its function investigated by knockdown and genome editing in 3T3-L1 cells. Adipogenesis was assessed by oil red O staining of neutral cell lipids and production of established marker and regulator proteins. siRNA-mediated knockdown significantly reduced

Indexed as

3T3-L1 CellsActin CytoskeletonActinsAdipocytesAdipogenesisAnimalsCell DifferentiationCollagen Type IIIExtracellular MatrixGene EditingLigandsMicePhenotypeReceptors, G-Protein-CoupledStress FibersActinsAdgrg1 protein, mouseCOL3A1 protein, mouseCollagen Type IIILigandsReceptors, G-Protein-Coupledactin cytoskeletonadipogenesisCOL3A1extracellular matrixgenome editingtype III collagen

Identifiers

PMID33504048
PMCPMC7911635
OpenAlexW3123805106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.