Evidence map›Paper›PMID 33504033›Full record

ArticleNutrients2021

Parathyroid Hormone in Pregnancy: Vitamin D and Other Determinants.

Ola Hysaj, Patricia Marqués-Gallego, Aline Richard, Magdeldin Elgizouli, Alexandra Nieters, Katharina C Quack Lötscher, Sabine Rohrmann

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Vitamin and mineral levels during pregnancy.Revista da Associacao Medica Brasileira (1992) · 2022
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ola HysajEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.
Patricia Marqués-GallegoEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.
Aline RichardEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.
Magdeldin ElgizouliFREEZE-Biobank, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacherstr. 115 4, D-79106 Freiburg, Germany.
Alexandra NietersFREEZE-Biobank, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacherstr. 115 4, D-79106 Freiburg, Germany.
Katharina C Quack LötscherClinic of Obstetrics, University Hospital Zurich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland.
Sabine RohrmannEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.ORCID 0000-0002-2215-1200
University of Zurich · CHUniversity of Freiburg · DEUniversity Hospital of Zurich · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung NFP69 - No. 145194Swiss Government Excellence Scholarship ESKAS 2019.0438
6 · The paper itself

Abstract

We aimed to assess the parathyroid hormone (PTH) concentration in pregnant women at the beginning of pregnancy (1st trimester) and within days before delivery (3rd trimester) and evaluate its determinants. From September 2014 through December 2015 in a cross-sectional study, 204 women in the 1st trimester of pregnancy and 203 women in the 3rd trimester of pregnancy were recruited. Blood samples were collected to measure PTH and circulating 25-hydroxy-vitamin D (25(OH)D) concentrations. Lifestyle and demographic data were collected using a questionnaire. Serum 25(OH)D and PTH were inversely correlated in both early and late pregnancy. Our analyses suggest that in the 3rd trimester of pregnancy, a 25(OH)D level of 18.9 ng/mL (47.3 nmol/L) could serve as an inflection point for the maximal suppression of PTH. Statistically significant determinants of PTH concentrations in multiple regression were 25(OH)D concentrations, season, multiparity and education of the partner (all

Indexed as

AdultCross-Sectional StudiesFemaleHumansLife StyleParathyroid HormonePregnancyPregnancy Trimester, FirstPregnancy Trimester, ThirdSocioeconomic FactorsSwitzerlandVitamin DVitaminsYoung AdultParathyroid HormoneVitamin DVitaminsdeterminantsparathyroid hormonepregnancyvitamin D

Identifiers

PMID33504033
PMCPMC7911996
OpenAlexW3123862397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.