ArticleBiology2021
Coronavirus Disease 2019 (COVID-19) in Italy: Double Reading of Chest CT Examination.
Article in Biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Thoracic imaging tests for the diagnosis of COVID-19.The Cochrane database of systematic reviews · 2022Pooled it
- AI-Based HRCT Quantification in Connective Tissue Disease-Associated Interstitial Lung Disease.Diagnostics (Basel, Switzerland) · 2025Article
- Diagnostic Efficacy of Chest Computed Tomography with a Dual-Reviewer Approach in Patients Diagnosed with Pneumonia Secondary to Severe Acute Respiratory Syndrome Coronavirus 2.Tomography (Ann Arbor, Mich.) · 2023Observational
- Qualitative and semi-quantitative ultrasound assessment in delta and Omicron Covid-19 patients: data from high volume reference center.Infectious agents and cancer · 2023Article
- CARdioimaging in Lung Cancer PatiEnts Undergoing Radical RadioTherapy: CARE-RT Trial.Diagnostics (Basel, Switzerland) · 2023Article
- Radiation Recall Pneumonitis: The Open Challenge in Differential Diagnosis of Pneumonia Induced by Oncological Treatments.Journal of clinical medicine · 2023Review
- Robustness of Radiomics in Pre-Surgical Computer Tomography of Non-Small-Cell Lung Cancer.Journal of personalized medicine · 2022Article
- Coronavirus Disease 2019 (COVID-19).Biology · 2022Article
- Imaging Severity COVID-19 Assessment in Vaccinated and Unvaccinated Patients: Comparison of the Different Variants in a High Volume Italian Reference Center.Journal of personalized medicine · 2022Article
- Pulmonary Lymphangitis Poses a Major Challenge for Radiologists in an Oncological Setting during the COVID-19 Pandemic.Journal of personalized medicine · 2022Article
- Not only lymphadenopathy: case of chest lymphangitis assessed with MRI after COVID 19 vaccine.Infectious agents and cancer · 2022Article
- Chest CT texture-based radiomics analysis in differentiating COVID-19 from other interstitial pneumonia.La Radiologia medica · 2021Article
- Quantitative Analysis of Residual COVID-19 Lung CT Features: Consistency among Two Commercial Software.Journal of personalized medicine · 2021Article
- Artificial Intelligence and COVID-19 Using Chest CT Scan and Chest X-ray Images: Machine Learning and Deep Learning Approaches for Diagnosis and Treatment.Journal of personalized medicine · 2021Review
- Evolution of CT Findings and Lung Residue in Patients with COVID-19 Pneumonia: Quantitative Analysis of the Disease with a Computer Automatic Tool.Journal of personalized medicine · 2021Article
- Breast Cancer Screening during COVID-19 Emergency: Patients and Department Management in a Local Experience.Journal of personalized medicine · 2021Article
- A Rare Case of Cerebral Venous Thrombosis and Disseminated Intravascular Coagulation Temporally Associated to the COVID-19 Vaccine Administration.Journal of personalized medicine · 2021Article
- Lymphadenopathy afterBiology · 2021Article
- On the Adoption of Radiomics and Formal Methods for COVID-19 Coronavirus Diagnosis.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess the performance of the second reading of chest compute tomography (CT) examinations by expert radiologists in patients with discordance between the reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test for COVID-19 viral pneumonia and the CT report. Three hundred and seventy-eight patients were included in this retrospective study (121 women and 257 men; 71 years median age, with a range of 29-93 years) and subjected to RT-PCR tests for suspicious COVID-19 infection. All patients were subjected to CT examination in order to evaluate the pulmonary disease involvement by COVID-19. CT images were reviewed first by two radiologists who identified COVID-19 typical CT patterns and then reanalyzed by another two radiologists using a CT structured report for COVID-19 diagnosis. Weighted к values were used to evaluate the inter-reader agreement. The median temporal window between RT-PCRs execution and CT scan was zero days with a range of (-9,11) days. The RT-PCR test was positive in 328/378 (86.8%). Discordance between RT-PCR and CT findings for viral pneumonia was revealed in 60 cases. The second reading changed the CT diagnosis in 16/60 (26.7%) cases contributing to an increase the concordance with the RT-PCR. Among these 60 cases, eight were false negative with positive RT-PCR, and 36 were false positive with negative RT-PCR. Sensitivity, specificity, positive predictive value and negative predictive value of CT were respectively of 97.3%, 53.8%, 89.0%, and 88.4%. Double reading of CT scans and expert second readers could increase the diagnostic confidence of radiological interpretation in COVID-19 patients.
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