ReviewJournal of clinical medicine2021
Ventricular Assist Device-Specific Infections.
Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Minimally Invasive Left Ventricular Assist Device Implantation: A Systematic Review of Current Evidence on Clinical Outcomes and Surgical Approaches.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Handheld infrared thermography for triage of LVAD driveline infection: A prospective pilot diagnostic accuracy study.JHLT open · 2026Article
- Material-Driven Clinical Complications in Mechanical Circulatory Support: From Blood-Material Interactions to Device-Related Adverse Events.Materials (Basel, Switzerland) · 2026Review
- Using biofilm-targeting local antibiotics to treat recalcitrant medical device-associated infections: driveline infection as a model.The Journal of antimicrobial chemotherapy · 2026Article
- Long-term outcomes of patients implanted with a HeartMate 3 left ventricular assist device-a real-world, single-centre, observational study.ESC heart failure · 2026Observational
- Article
- Addressing Complications in Cardiac Implantable Electronic Devices: A Guideline to Prevention of CIED Infection.Journal of cardiovascular development and disease · 2025Review
- Local Infections Associated with Ventricular Assist Devices: Materials-Related Challenges and Emerging Solutions.Materials (Basel, Switzerland) · 2025Review
- A simple silicone elastomer colonization model highlights complexities ofJournal of medical microbiology · 2025Article
- Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices.JHLT open · 2025Article
- Outcomes of Left Ventricular Assist Devices as Destination Therapy: A Systematic Review with Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Survival of a patient following initial left ventricular assist device implantation and two successive left ventricular assist device exchanges: case report.European heart journal. Case reports · 2024Article
- Infections in Patients with Mechanical Circulatory Support.Infectious disease clinics of North America · 2024Review
- Outcome Through the Years of Left-Ventricular Assist Devices Therapy for End-Stage Heart Failure: A Review.Journal of clinical medicine · 2024Review
- Heartware ventricular assist device versus HeartMate II versus HeartMate III in advanced heart failure patients: A systematic review and meta-analysis.SAGE open medicine · 2024Review
- Time-lapse mesoscopy ofMicrobiology (Reading, England) · 2024Article
- Anti-infective characteristics of a new Carbothane ventricular assist device driveline.Biofilm · 2023Article
- Systems of conductive skin for power transfer in clinical applications.European biophysics journal : EBJ · 2022Review
- Driveline Features as Risk Factor for Infection in Left Ventricular Assist Devices: Meta-Analysis and Experimental Tests.Frontiers in cardiovascular medicine · 2021Article
- Surgically Managed Deep Sternal Wound Infection After Heart Transplantation.Transplant infectious disease : an official journal of the Transplantation SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Ventricular assist device (VAD)-specific infections, in particular, driveline infections, are a concerning complication of VAD implantation that often results in significant morbidity and even mortality. The presence of a percutaneous driveline at the skin exit-site and in the subcutaneous tunnel allows biofilm formation and migration by many bacterial and fungal pathogens. Biofilm formation is an important microbial strategy, providing a shield against antimicrobial treatment and human immune responses; biofilm migration facilitates the extension of infection to deeper tissues such as the pump pocket and the bloodstream. Despite the introduction of multiple preventative strategies, driveline infections still occur with a high prevalence of ~10-20% per year and their treatment outcomes are frequently unsatisfactory. Clinical diagnosis, prevention and management of driveline infections are being targeted to specific microbial pathogens grown as biofilms at the driveline exit-site or in the driveline tunnel. The purpose of this review is to improve the understanding of VAD-specific infections, from basic "bench" knowledge to clinical "bedside" experience, with a specific focus on the role of biofilms in driveline infections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.