Evidence map›Paper›PMID 33503882›Full record

Trial reportNutrients2021

Cortical Oxygenation Changes during Gastric Tube Feeding in Moderate- and Late-Preterm Babies: A NIRS Study.

Mariana Muelbert, Tanith Alexander, Chris Pook, Yannan Jiang, Jane Elizabeth Harding, Frank Harry Bloomfield

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06706115 (), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06706115 narecruitingnot on this mapstarted 2024, after this paper: background citation

: Effect of Intranasal Breast Milk Administration on Cerebral Oxygenation, Vital Signs and Transition Time to Full Oral Feeding in Preterm Babies: Randomized Controlled Study

TypeinterventionalSponsorSelcuk UniversityRan2024 to 2025Enrolled40ConditionsNewborn, Vitality, Nursing Caries, Breast FeedingArmsIntranasal human breast milk
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mariana MuelbertLiggins Institute, University of Auckland, 1142 Auckland, New Zealand.ORCID 0000-0002-9551-4869
Tanith AlexanderLiggins Institute, University of Auckland, 1142 Auckland, New Zealand.
Chris PookLiggins Institute, University of Auckland, 1142 Auckland, New Zealand.ORCID 0000-0002-0932-1965
Yannan JiangLiggins Institute, University of Auckland, 1142 Auckland, New Zealand.
Jane Elizabeth HardingLiggins Institute, University of Auckland, 1142 Auckland, New Zealand.ORCID 0000-0003-2697-1422
Frank Harry BloomfieldLiggins Institute, University of Auckland, 1142 Auckland, New Zealand.ORCID 0000-0001-6424-6577
University of Auckland · NZ

Funding

Health Research Council of New Zealand 16/605University of Auckland University of Auckland Doctoral Scholarship
6 · The paper itself

Abstract

Smell and taste of food can trigger physiological responses facilitating digestion and metabolism of nutrients. Controlled experimental studies in preterm babies have demonstrated that smell activates the orbitofrontal cortex (OFC) but none have investigated the effect of taste stimulation. Using cotside Near-Infrared Spectroscopy (NIRS), we measured changes in OFC cerebral oxygenation in response to gastric tube feeds five and 10 days after birth in 53 assessments of 35 moderate- to late-preterm babies enrolled in a randomized trial. Babies were randomly assigned to receive smell and taste of milk before gastric tube feeds (intervention group,

Indexed as

Olfactory PerceptionTaste PerceptionCohort StudiesEnteral NutritionFemaleHumansInfant, NewbornInfant, PrematureMaleOxygenPrefrontal CortexPremature BirthSpectroscopy, Near-InfraredOxygencortical activationmilkmoderate and late pretermnear-infrared spectroscopynutritionsensory stimulationsmelltastetube feeding

Identifiers

PMID33503882
PMCPMC7911983
OpenAlexW3125104374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.