Evidence map›Paper›PMID 33503848›Full record

ArticlePathogens (Basel, Switzerland)2021

Participation of Central Muscarinic Receptors on the Nervous Form of Chagas Disease in Mice Infected via Intracerebroventricular with Colombian

Gabriela Maira Pereira de Assis, Micheline Freire Donato, Matheus Marques Milagre, Samantha Ribeiro Béla, Mayra Fernanda Ricci, Luara Augusta Batista, Maria Elena de Lima, Fabrício de Araujo Moreira, Rosa Maria Esteves Arantes, Marta de Lana

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Current tropical medicine reports · 2023
    Article
  3. Host-Pathogen Interaction Involved inPathogens (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Gabriela Maira Pereira de AssisPrograma de Pós-Graduação em Ciências Biológicas (CBIOL), Núcleo de Pesquisas em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto (UFOP), 35400-000 Ouro Preto, Brazil.ORCID 0000-0002-1288-4689
Micheline Freire DonatoPrograma de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos (PGPNSB), Universidade Federal da Paraíba (UFPB), 58010-340 João Pessoa, Brazil.
Matheus Marques MilagrePrograma de Pós-Graduação em Ciências Farmacêuticas (CiPHARMA), Escola de Farmácia, Universidade Federal de Ouro Preto (UFOP), 35400-000 Ouro Preto, Brazil.ORCID 0000-0002-7289-4651
Samantha Ribeiro BélaPrograma de Pós-Graduação em Ciências Biológicas (CBIOL), Núcleo de Pesquisas em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto (UFOP), 35400-000 Ouro Preto, Brazil.ORCID 0000-0002-2331-8009
Mayra Fernanda RicciDepartamento de Patologia Geral, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais (UFMG), 31660-060 Belo Horizonte, Brazil.
Luara Augusta BatistaPrograma de Pós Graduação em Neurociência, Departamento de Farmacologia, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais (UFMG), 31660-060 Belo Horizonte, Brazil.ORCID 0000-0002-6183-993X
Maria Elena de LimaSanta Casa de Belo Horizonte: Instituto de Ensino e Pesquisa, 30150-240 Belo Horizonte, Brazil.ORCID 0000-0001-6185-4032
Fabrício de Araujo MoreiraPrograma de Pós Graduação em Neurociência, Departamento de Farmacologia, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais (UFMG), 31660-060 Belo Horizonte, Brazil.
Rosa Maria Esteves ArantesDepartamento de Patologia Geral, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais (UFMG), 31660-060 Belo Horizonte, Brazil.ORCID 0000-0003-1428-9717
Marta de LanaPrograma de Pós-Graduação em Ciências Biológicas (CBIOL), Núcleo de Pesquisas em Ciências Biológicas (NUPEB), Universidade Federal de Ouro Preto (UFOP), 35400-000 Ouro Preto, Brazil.ORCID 0000-0002-1565-4707
Universidade Federal de Minas Gerais · BRUniversidade Federal de Ouro Preto · BRInstituto de Ensino e Pesquisa Santa Casa · BRUniversidade Federal da Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute chagasic encephalitis is a clinically severe central nervous system (CNS) manifestation. However, the knowledge of the nervous form of Chagas disease is incomplete. The role of the muscarinic acetylcholine receptor (mAChR) on mice behavior and brain lesions induced by

Indexed as

infection evolutionmuscarinic cholinergic pathwaynervous Chagas disease

Identifiers

PMID33503848
PMCPMC7922850
OpenAlexW3121637172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.