Evidence map›Paper›PMID 33503216›Full record

ArticleActa cirurgica brasileira2021

Age-dependent histomorphometric evolution of the corpus spongiosum.

Gino Pigatto Filho, Marcelo Zeni, Eduardo Felippe Melchioretto, Gustavo Lenci Marques, Thiago Hota, Rogério de Fraga

Open access · goldAbstract read
In one paragraph

Article in Acta cirurgica brasileira, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gino Pigatto FilhoFellow Master degree, Postgraduate Program in Surgical Clinic, Universidade Federal do Paraná, Curitiba-PR, Brazil.ORCID http://orcid.org/0000-0002-1656-712X
Marcelo ZeniMsc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil.ORCID http://orcid.org/0000-0002-3072-2106
Eduardo Felippe MelchiorettoMsc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil.ORCID http://orcid.org/0000-0003-2911-2850
Gustavo Lenci MarquesMsc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil.ORCID http://orcid.org/0000-0002-6057-0350
Thiago HotaMsc, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil.ORCID http://orcid.org/0000-0003-4544-0539
Rogério de FragaPhD, Department of Clinical Surgery, Health Sciences Sector, Universidade Federal do Paraná, Curitiba-PR, Brazil.ORCID http://orcid.org/0000-0002-9012-3922
Universidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo quantify the age-dependent changes in the relative volume of elastic fibers, collagen fibers and the proportion of collagen types I/III in the corpus spongiosum of rats.

methodsForty-eight rats, raised under similar conditions, were divided into four groups (G1 to G4) and underwent penectomy at the ages of 6, 9, 12 and 24 months, respectively. Histological sections from the middle segment of the penis were stained with Weigert's resorcin-fuchsin, Masson's trichrome and Picrosirius red, the volumetric density of elastic fibers, collagen fibers and the proportion of collagen types I and III in the corpus spongiosum were determined by stereological analysis.

resultsA reduction in the proportion of collagen I/III between the groups G3 and G4 (p < 0.048) was observed. In the volumetric analysis of elastic fiber, we observed a significant rise between the groups G2 and G3 (p < 0.03) and a reduction of the volume between the groups G3 and G4 (p < 0.01). However, there was no difference in the quantity of total collagen between the groups (p > 0.54).

conclusionsAging in rats did not change the quantity of total collagen but reduced the proportion of collagen types I/III and the volume of elastic fibers.

Indexed as

Elastic TissuePenisAgingAnimalsCollagenCollagen Type IMaleRatsCollagenCollagen Type I

Identifiers

PMID33503216
PMCPMC7819684
OpenAlexW3122485767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.