Evidence map›Paper›PMID 33502723›Full record

ArticleJournal of applied genetics2021

Endemicity of OXA-23 and OXA-72 in clinical isolates of Acinetobacter baumannii from three neighbouring countries in Southeast Europe.

Ivana Goic-Barisic, Ana Kovacic, Deana Medic, Sanja Jakovac, Tanja Petrovic, Marija Tonkic, Anita Novak, Zana Rubic, Marina Radic, Biljana Milosavljević and 1 more

Abstract read
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Article in Journal of applied genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Antimicrobial Resistance and Virulence ofAntibiotics (Basel, Switzerland) · 2026
    Article
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  3. Carbapenem-ResistantMicroorganisms · 2026
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  4. Article
  5. Treatment-emergent cefiderocol resistance in carbapenem-resistantAntimicrobial agents and chemotherapy · 2024
    Article
  6. Genomic study ofFrontiers in microbiology · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Ivana Goic-BarisicUniversity of Split School of Medicine, HR-21000, Split, Croatia. igoic@kbsplit.hr.ORCID http://orcid.org/0000-0002-1030-6092
Ana KovacicInstitute of Public Health of Split and Dalmatia Country, Split, Croatia.
Deana MedicFaculty of Medicine, University of Novi Sad, Novi Sad, Serbia.
Sanja JakovacUniversity Clinical Hospital of Mostar and University of Mostar School of Medicine, Mostar, Bosnia and Herzegovina.
Tanja PetrovicUniversity Clinical Hospital of Mostar and University of Mostar School of Medicine, Mostar, Bosnia and Herzegovina.
Marija TonkicUniversity of Split School of Medicine, HR-21000, Split, Croatia.
Anita NovakUniversity of Split School of Medicine, HR-21000, Split, Croatia.
Zana RubicUniversity of Split School of Medicine, HR-21000, Split, Croatia.
Marina RadicUniversity of Split School of Medicine, HR-21000, Split, Croatia.
Biljana MilosavljevićInstitute of Public Health of Vojvodina, Novi Sad, Serbia.
Jasna HrenovicDepartment of Biology, Faculty of Science, University of Zagreb, Zagreb, Croatia.
University of Split · HRUniversity of Mostar · BACroatian Hydrographic Institute · HRInstitute of Public Health of Vojvodina · RSUniversity of Novi Sad · RSUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the World Health Organization, bacterium Acinetobacter baumannii is the first on the critical priority list of pathogens in urgent need for new antibiotics. The increasing resistance of A. baumannii to the last-line treatment options, including carbapenems, is a global problem. We report the molecular epidemiology of 12 carbapenem-resistant clinical isolates of A. baumannii collected from hospitalised patients in three neighbouring countries in Southeast Europe: Croatia, Serbia, and Bosnia and Herzegovina, giving an insight into the molecular characterisation and evolutionary history of the acquisition of resistance genes. Besides the blaOXA-23 gene, the endemic presence of OXA-72 oxacillinase of the same origin for more than a decade as the leading mechanism of carbapenem resistance in Southeast Europe was confirmed. To the best of our knowledge, this is the first paper that investigates and analyses the phylogenetic association of the most common mechanisms of resistance to carbapenems in clinical isolates of A. baumannii originating from three neighbouring countries in Southeast Europe.

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsDrug Resistance, BacterialEuropeHumansMicrobial Sensitivity TestsPhylogenyAnti-Bacterial AgentsBacterial Proteinsbeta-lactamase OXA-23beta-LactamasesCarbapenemsOXA-72 carbapenemase, Acinetobacter baumanniiAcinetobacter baumanniiBosnia and HerzegovinaCroatiaEndemic oxacillinaseSerbia

Identifiers

PMID33502723
OpenAlexW3123821499

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.