Evidence map›Paper›PMID 33502648›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2021

How to optimize administration of cefoxitin for the treatment of extended spectrum producing Enterobacteriaceae-related infection?

Benoît Pilmis, Assaf Mizrahi, Céline Mory, Alban Le Monnier, Najoua El Helali

Abstract read
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Benoît PilmisÉquipe mobile de microbiologie clinique, Groupe Hospitalier Paris Saint-Joseph, 185 rue Raymond Losserand, 75015, Paris, France. bpilmis@hpsj.fr.
Assaf MizrahiBactéries Pathogènes et Santé, Institut Micalis, UMR 1319, INRAe, AgroParisTech, Université Paris-Saclay, Paris, France.
Céline MoryPlateforme de dosage des anti-infectieux, Groupe Hospitalier Paris Saint-Joseph, Paris, France.
Alban Le MonnierBactéries Pathogènes et Santé, Institut Micalis, UMR 1319, INRAe, AgroParisTech, Université Paris-Saclay, Paris, France.
Najoua El HelaliService de microbiologie clinique, Groupe Hospitalier Paris Saint-Joseph, Paris, France.
Hôpital Paris Saint-Joseph · FRMicrobiologie de l’alimentation au service de la santé · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmacological and clinical data regarding cefoxitin for the treatment of ESBL-producing Enterobacteriaceae-related infections are limited. We performed a multicentric prospective cohort study to evaluate continuous/prolonged, or intermittent infusion of cefoxitin. We assessed the plasma concentration as a function of the duration of infusion and then performed a simulation of the percentage of patients who would reach the PK/PD targets, set at 100% ƒT

Indexed as

AgedAnti-Bacterial Agentsbeta-LactamasesCefoxitinDrug MonitoringDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial Agentsbeta-LactamasesCefoxitinCefoxitinESBLPK/PD

Identifiers

PMID33502648
OpenAlexW3125635948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.