SynthesisInternational journal of clinical oncology2021
Adherent perinephric fat affects perioperative outcomes after partial nephrectomy: a systematic review and meta-analysis.
Synthesis in International journal of clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 17 citations in OpenAlex.
- Adherent Perinephric Fat and Positive Surgical Margin in Laparoscopic Partial Nephrectomy: A Technique-Conditional Association Concentrated in Enucleation.Journal of clinical medicine · 2026Article
- Metabolic insights and novel risk score for adherent perinephric fat in partial nephrectomy: results from a prospective study.International urology and nephrology · 2026Article
- Body composition and renal cell carcinoma prognosis in elderly patients: a retrospective cohort study.BMC urology · 2026Article
- Mayo adhesive probability score predicts perioperative outcomes of laparoscopic adrenalectomy: a systematic review and meta-analysis.Frontiers in oncology · 2026Review
- Oncological Results After Accidental Tumor Incision During Partial Nephrectomy.European urology open science · 2026Article
- Evaluation of factors predicting adherent perinephric fat in laparoscopic retroperitoenal partial nephrectomy.BMC urology · 2025Article
- Is early-life obesity associated with kidney cancer in adulthood?-insights from genetic studies.Translational andrology and urology · 2025Article
- Article
- Clinical predictors and significance of adherent periadrenal fat in laparoscopic adrenalectomy.BMC urology · 2023Article
- Positive surgical margin's impact on short-term oncological prognosis after robot-assisted partial nephrectomy (MARGINS study: UroCCR no 96).Scientific reports · 2022Observational
- The evolving view of thermogenic fat and its implications in cancer and metabolic diseases.Signal transduction and targeted therapy · 2022Review
- Predicting the WHO/ISUP Grade of Clear Cell Renal Cell Carcinoma Through CT-Based Tumoral and Peritumoral Radiomics.Frontiers in oncology · 2022Article
- Clinical Implication of Adherent Perinephric Fat in Robot-Assisted Partial Nephrectomy: Validation With Video Review.Frontiers in surgery · 2022Article
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Authors and funding
14 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the association of adherent perinephric fat (APF) with perioperative outcomes, we conducted a systematic review and meta-analysis of the literature to clarify the impact of APF in patients undergoing partial nephrectomy. A systematic literature search using the Medline, Scopus, and Cochrane databases was performed in April 2019 and updated in November 2019 to identify studies investigating the effect of APF on perioperative outcomes in patients treated with partial nephrectomy with the aim of evaluating its impact on intraoperative, postoperative and oncological outcomes. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the included studies. A total of 1534 patients in nine nonrandomized, observational studies met our inclusion criteria. Patients with APF were significantly older (p = 0.0001), had a higher BMI (p = 0.0001) and were predominately male (p = 0.003). APF was associated with a higher operative time (p = 0.001) and higher blood loss (p = 0.002). No significant impact of APF was found in terms of postoperative complications, positive margins or length of stay. APF was also found to be associated with malignant renal histology of RCC on final pathology (p = 0.005). APF was associated with some adverse perioperative outcomes, especially a prolonged operating time and higher blood loss. In addition, APF was also associated with underlying renal malignancy, but the precise causal mechanism requires further exploration.
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