Evidence map›Paper›PMID 33502194›Full record

ArticleInorganic chemistry2021

Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences.

Ana Zamora, Erin Wachter, María Vera, David K Heidary, Venancio Rodríguez, Enrique Ortega, Vanesa Fernández-Espín, Christoph Janiak, Edith C Glazer, Giampaolo Barone and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Inorganic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Anticancer Activity of Nonpolar Pt(CHJournal of molecular structure · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Ana ZamoraDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.ORCID http://orcid.org/0000-0001-7013-8900
Erin WachterDepartment of Chemistry, University of Kentucky 505 Rose Street, Lexington, Kentucky 40506, United States.
María VeraDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.
David K HeidaryDepartment of Chemistry, University of Kentucky 505 Rose Street, Lexington, Kentucky 40506, United States.
Venancio RodríguezDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.
Enrique OrtegaDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.
Vanesa Fernández-EspínDepartamento de Química Física, Universidad de Murcia, E-30071 Murcia, Spain.
Christoph JaniakInstitut für Anorganische Chemie und Strukturchemie, Heinrich-Heine-Universität Düsseldorf, D-40204 Düsseldorf, Germany.
Edith C GlazerDepartment of Chemistry, University of Kentucky 505 Rose Street, Lexington, Kentucky 40506, United States.ORCID http://orcid.org/0000-0002-0190-7742
Giampaolo BaroneDipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, 90128 Palermo, Italy.ORCID http://orcid.org/0000-0001-8773-2359
José RuizDepartamento de Química Inorgánica, Universidad de Murcia, and Biomedical Research Institute of Murcia (IMIB-Arrixaca), E-30071 Murcia, Spain.ORCID http://orcid.org/0000-0002-0834-337X
Universidad de Murcia · ESUniversity of Kentucky · USHeinrich Heine University Düsseldorf · DEUniversity of Palermo · IT

Funding

Light-responsive ruthenium compounds for applications in diseaseR01GM107586 · NIGMS · UNIVERSITY OF KENTUCKY · PI GLAZER, EDITH C · 2014 to 2019
$1.7M
NIGMS NIH HHS R01 GM107586
6 · The paper itself

Abstract

The specific recognition of AT-rich DNA sequences opens up the door to promising diagnostic and/or therapeutic strategies against gene-related diseases. Here, we demonstrate that amphiphilic Pt

Indexed as

A549 CellsCoordination ComplexesCrystallography, X-RayDNAElectrophoretic Mobility Shift AssayHumansIntercalating AgentsLigandsMolecular StructureOrganoplatinum CompoundsSpectrum AnalysisStereoisomerismCoordination ComplexesDNAIntercalating AgentsLigandsOrganoplatinum Compounds

Identifiers

PMID33502194
PMCPMC8456496
OpenAlexW3125869484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.