Evidence map›Paper›PMID 33501867›Full record

ArticleDrug delivery2021

Local anesthetic lidocaine-encapsulated polymyxin-chitosan nanoparticles delivery for wound healing:

Yanyan Qi, Xiangyan Yao, Xianhui Du, Songtao An

RetractedAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Pharmaceutics · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

  • Retraction · 2023-01-18Author Unresponsive · Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Referencing/Attributions · Lack of IRB/IACUC Approval and/or Compliance ·
  • Retracted
5 · Who and what money

Authors and funding

4 authors.

Yanyan QiDepartment of Anesthesiology, Henan Province People's Hospital, Zhengzhou, China.
Xiangyan YaoDepartment of Anesthesiology, Henan Province People's Hospital, Zhengzhou, China.
Xianhui DuDepartment of Anesthesiology, Henan Province People's Hospital, Zhengzhou, China.
Songtao AnDepartment of Cardiology, Fuwai Central Cardiovascular Hospital, Henan Provincial People's Hospital, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In relieving local pains, lidocaine, one of ester-type local anesthetics, has been used. To develop the lidocaine membranes of enhanced local anesthetic effects, we have designed to establish the composition of wound dressings based on lidocaine chloride (LCH) (anesthetic drug)-loaded chitosan (CS)/polymyxin B sulfate (PMB). The LCH membranes (LCH-CS/PMB) was fabricated by the LCH oxide solutions within the CS/PMB matrix. The influences of different experimental limitations on CS/PMB membrane formations were examined. The double membrane particle sizes were evaluated by scanning electron microscopy (HR-SEM). Additionally, antibacterial efficacy was developed for gram-positive and negative microorganisms. Moreover, we examined

Indexed as

ChitosanGuided Tissue RegenerationNanoparticlesAnesthetics, LocalAnimalsAnti-Bacterial AgentsBandagesBiocompatible MaterialsIn Vitro TechniquesLidocaineMechanical TestsMicePolymyxin BTissue ScaffoldsWound HealingAnesthetics, LocalAnti-Bacterial AgentsBiocompatible MaterialsChitosanLidocainePolymyxin Bchitosan/polymyxin Bin vivo mouse modelLidocaine chloridewound healing

Identifiers

PMID33501867
PMCPMC7850372

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.