Evidence map›Paper›PMID 33501427›Full record

ArticleBrain communications2021

Altered white matter microstructure is related to cognition in adults with congenital heart disease.

Melanie Ehrler, Ladina Schlosser, Peter Brugger, Matthias Greutmann, Angela Oxenius, Raimund Kottke, Ruth O'Gorman Tuura, Beatrice Latal

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Melanie EhrlerChild Development Center, University Children's Hospital Zurich, Zurich, Switzerland.ORCID 0000-0003-4253-2016
Ladina SchlosserChild Development Center, University Children's Hospital Zurich, Zurich, Switzerland.
Peter BruggerDepartment of Psychiatry, University Hospital Zurich, Zurich, Switzerland.
Matthias GreutmannDepartment of Cardiology, University Heart Center, University of Zurich, Zurich, Switzerland.
Angela OxeniusDepartment of Cardiology, University Heart Center, University of Zurich, Zurich, Switzerland.
Raimund KottkeDepartment of Diagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland.
Ruth O'Gorman TuuraChildren's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
Beatrice LatalChild Development Center, University Children's Hospital Zurich, Zurich, Switzerland.
University Children's Hospital Zurich · CHUniversity of Zurich · CHUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adults with congenital heart disease are at risk for persisting executive function deficits, which are known to affect academic achievement and quality of life. Alterations in white -matter microstructure are associated with cognitive impairments in adolescents with congenital heart disease. This study aimed to identify microstructural alterations potentially associated with executive function deficits in adults with congenital heart disease. Diffusion tensor imaging and tract-based spatial statistics were conducted in 45 patients (18 females) and 54 healthy controls (26 females) aged 18-32 years. Fractional anisotropy of white matter diffusion was compared between groups and correlated with an executive function score, derived from an extensive neuropsychological test battery. Patients showed widespread bilateral reduction in fractional anisotropy (

Indexed as

cognitioncongenital heart diseasediffusion tensor imagingexecutive functionwhite matter microstructure

Identifiers

PMID33501427
PMCPMC7811757
OpenAlexW3117108707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.