ArticleTheranostics2021
CCL16 maintains stem cell-like properties in breast cancer by activating CCR2/GSK3β/β-catenin/OCT4 axis.
Erratum issuedOpen access · goldAbstract read
In one paragraph
Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.
0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 38 citations in OpenAlex.
- Effective treatment of human breast tumors by chimeric CCL2 and CCL8 diphtheria toxin cytotoxic peptides.Cancer biology & therapy · 2026Article
- PRTN3 drives immunosuppression in KRAS-mutant lung adenocarcinoma through proteolytic inactivation of CXCL9.Journal for immunotherapy of cancer · 2026Article
- Clinical applications of immunogenomics in hepatocellular carcinoma.Clinical and molecular hepatology · 2026Review
- Article
- The chemokine network in triple-negative breast cancer: its role in immune microenvironment regulation, and prospects for targeted therapy.Frontiers in immunology · 2026Review
- Innate immune signaling-driven myeloid remodeling in cancer: inflammatory amplification, immune suppression, and therapeutic targeting.Frontiers in immunology · 2026Review
- Fueling the Seed: Growth Factors and Cytokines Driving Cancer Stem Cells in Gynecological Malignancies.International journal of molecular sciences · 2025Review
- Transformable self-assembling peptide nanoplatforms with tumor microenvironment responsiveness for tumor stem cell suppression and immunomodulation.Materials today. Bio · 2025Article
- Therapeutic and Prognostic Relevance of Cancer Stem Cell Populations in Endometrial Cancer: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Unlocking the Role of OCT4 in Cancer Lineage Plasticity: A Cross-Cancer Perspective with an Emphasis on Prostate Cancer.Biomedicines · 2025Review
- Article
- Synthesis of a novel mitochondrial fluorescent probe - killing cancer cellsFrontiers in pharmacology · 2025Article
- PDPN/CCL2/STAT3 feedback loop alter CAF heterogeneity to promote angiogenesis in colorectal cancer.Angiogenesis · 2024Article
- Article
- Transcriptional regulation of cancer stem cell: regulatory factors elucidation and cancer treatment strategies.Journal of experimental & clinical cancer research : CR · 2024Review
- CCL16 is a pro-tumor chemokine that recruits monocytes and macrophages to promote hepatocellular carcinoma progression.American journal of cancer research · 2024Article
- TBX21 attenuates colorectal cancer progression via an ARHGAP29/RSK/GSK3β dependent manner.Cellular oncology (Dordrecht, Netherlands) · 2023Article
- Cross talk between tumor stemness and microenvironment for prognosis and immunotherapy of uveal melanoma.Journal of cancer research and clinical oncology · 2023Article
- Article
- Review
Corrections and comments
- Erratum issued
Authors and funding
16 authors at 5 institutions in 1 country.
Wenzhi ShenDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Xiaoyuan ZhangDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Jiaping TangDept. of Anatomy and Histology, School of Medicine, Nankai University, Tianjin 300071, China.
Zhixin ZhangDept. of Gastrointestinal Surgery, Affiliated Hospital of Jining Medical University, Jining 272029, China.
Renle DuDept. of Immunology, School of Medicine, Nankai University, Tianjin 300071, China.
Dehong LuoThe First People's Hospital of Zunyi, Zunyi, 563002, China.
Xiaoran LiuDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Yong XiaDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Yanping LiDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Shanshan WangDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Siyuan YanDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Wancai YangDept. of Pathology and Institute of Precision Medicine, Jining Medical University, Jining 272067, China.
Rong XiangDept. of Immunology, School of Medicine, Nankai University, Tianjin 300071, China.
Na LuoDept. of Anatomy and Histology, School of Medicine, Nankai University, Tianjin 300071, China.
Yunping LuoDept. of Immunology, Institute of Basic Medical Science, Chinese Academy of Medical Science, School of Basic Medicine Peking Union Medical College, Beijing, 100005, China.
Jianjun LiInstitute of Breast Research, Jining Medical University, Jining 272067, China.
Jining Medical University · CNNankai University · CNAffiliated Hospital of Jining Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFirst People’s Hospital of Zunyi · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsApoptosisbeta CateninBiomarkers, TumorBreast NeoplasmsCell ProliferationChemokines, CCFemaleGene Expression Regulation, NeoplasticGlycogen Synthase Kinase 3 betaHumansMiceMice, Inbred NODMice, SCIDNeoplastic Stem CellsOctamer Transcription Factor-3beta CateninBiomarkers, TumorCCL16 protein, humanCCR2 protein, humanChemokines, CCCTNNB1 protein, humanGlycogen Synthase Kinase 3 betaOctamer Transcription Factor-3POU5F1 protein, humanReceptors, CCR2breast cancerCCL16CCR2CSCsOCT4β-catenin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.