Evidence map›Paper›PMID 33500706›Full record

ArticleTheranostics2021

Imaging temozolomide-induced changes in the myeloid glioma microenvironment.

Claudia Foray, Silvia Valtorta, Cristina Barca, Alexandra Winkeler, Wolfgang Roll, Michael Müther, Stefan Wagner, Miranda L Gardner, Sven Hermann, Michael Schäfers and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Tracking macrophages by direct and indirectEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. TSPO Radioligands for Neuroinflammation: An Overview.Molecules (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Article
  12. Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  13. Article
  14. TSPO PET signal using [European journal of nuclear medicine and molecular imaging · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. Interrogating Glioma-Associated Microglia and Macrophage Dynamics Under CSF-1R Therapy with Multitracer In Vivo PET/MRI.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Claudia ForayEuropean Institute for Molecular Imaging - EIMI, University of Münster, Münster, Germany.
Silvia ValtortaTecnomed Foundation and Medicine and Surgery Department, University of Milano-Bicocca, Milan, Italy.
Cristina BarcaEuropean Institute for Molecular Imaging - EIMI, University of Münster, Münster, Germany.
Alexandra WinkelerUniversité Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Orsay, France.
Wolfgang RollDepartment of Nuclear Medicine, University Hospital Münster, Münster, Germany.
Michael MütherDepartment of Neurosurgery, University Hospital Münster, Münster, Germany.
Stefan WagnerDepartment of Nuclear Medicine, University Hospital Münster, Münster, Germany.
Miranda L GardnerCampus Chemical Instrument Center, Mass Spectrometry and Proteomics Facility (CCIC-MSP), The Ohio State University, Columbus, OH, United States.
Sven HermannEuropean Institute for Molecular Imaging - EIMI, University of Münster, Münster, Germany.
Michael SchäfersEuropean Institute for Molecular Imaging - EIMI, University of Münster, Münster, Germany.
Oliver Martin GrauerDepartment of Neurology, University Hospital Münster, Münster, Germany.
Rosa Maria MorescoTecnomed Foundation and Medicine and Surgery Department, University of Milano-Bicocca, Milan, Italy.
Bastian ZinnhardtEuropean Institute for Molecular Imaging - EIMI, University of Münster, Münster, Germany.
Andreas H JacobsEuropean Institute for Molecular Imaging - EIMI, University of Münster, Münster, Germany.
University Hospital Münster · DEUniversity of Münster · DEInserm · FRIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleJohanniter-Krankenhaus Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Tumor MicroenvironmentAnimalsAntineoplastic Agents, AlkylatingApoptosisBrain NeoplasmsCell ProliferationFemaleGliomaHumansImage Processing, Computer-AssistedMicePositron-Emission TomographyTemozolomideTumor BurdenTumor Cells, CulturedXenograft Model Antitumor AssaysAntineoplastic Agents, AlkylatingTemozolomide[18F]DPA-714[18F]FETGAMMglioblastomatemozolomideTSPO

Identifiers

PMID33500706
PMCPMC7797694
OpenAlexW3113117461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.