Evidence map›Paper›PMID 33500660›Full record

ReviewCancer management and research2021

Trends in the Management of Non-Vestibular Skull Base and Intracranial Schwannomas.

Carlos Suárez, Fernando López, William M Mendenhall, Simon Andreasen, Lauge Hjorth Mikkelsen, Johannes A Langendijk, Stefano Bondi, Juan P Rodrigo, Leif Bäck, Antti A Mäkitie and 5 more

Abstract readReview
In one paragraph

Review in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Carlos SuárezInstituto de Investigación Sanitaria del Principado de Asturias and CIBERONC, ISCIII, Oviedo, Spain.
Fernando LópezInstituto de Investigación Sanitaria del Principado de Asturias and CIBERONC, ISCIII, Oviedo, Spain.ORCID 0000-0001-7019-9746
William M MendenhallDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA.
Simon AndreasenDepartment of Otorhinolaryngology Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen, Denmark.ORCID 0000-0002-1528-4988
Lauge Hjorth MikkelsenDepartment of Pathology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.ORCID 0000-0002-4110-6739
Johannes A LangendijkDepartment of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Stefano BondiDepartment of Otorhinolaryngology-Head and Neck Surgery, San Raffaele Hospital, Vita-Salute University, Milan, Italy.ORCID 0000-0002-9163-5540
Juan P RodrigoInstituto de Investigación Sanitaria del Principado de Asturias and CIBERONC, ISCIII, Oviedo, Spain.
Leif BäckDepartment of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0001-8383-7671
Antti A MäkitieDepartment of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.ORCID 0000-0002-0451-2404
Verónica Fernández-AlvarezVascular Surgery Department, Hospital Universitario Central de Asturias, Oviedo, Spain.ORCID 0000-0002-6345-9279
Andrés Coca-PelazInstituto de Investigación Sanitaria del Principado de Asturias and CIBERONC, ISCIII, Oviedo, Spain.ORCID 0000-0003-1363-8559
Robert SmeeDepartment of Radiation Oncology, The Prince of Wales Cancer Centre, Sydney, NSW, Australia.
Alessandra RinaldoUniversity of Udine School of Medicine, Udine, Italy.ORCID 0000-0001-7956-6709
Alfio FerlitoInternational Head and Neck Scientific Group, Padua, Italy.ORCID 0000-0002-8247-8002

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this review is to analyze the latest trends in the management of non-vestibular skull base and intracranial schwannomas in order to optimize tumor control and quality of life. Non-vestibular cranial nerve schwannomas are rare lesions, representing 5-10% of cranial nerve schwannomas. Management decisions should be individualized depending on tumor size, location and associated functional deficits. Generally, large sized schwannomas exerting significant mass effect with increased intracranial pressure are treated surgically. In some cases, even after optimal skull base resection, it is not possible to achieve a gross total resection because tumor location and extent and/or to reduce morbidity. Thus, subtotal resection followed by stereotactic radiosurgery or fractioned radiotherapy offers an alternative approach. In certain cases, stereotactic radiosurgery or radiotherapy alone achieves good tumor control rates and less morbidity to gross total resection. Finally, given the slow growth rate of most of these tumors, observation with periodic radiographic follow-up approach is also a reasonable alternative for small tumors with few, if any, symptoms.

Indexed as

cranial nerveshead and necknon-vestibularschwannomaskull base

Identifiers

PMID33500660
PMCPMC7822088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.