Evidence map›Paper›PMID 33500646›Full record

ArticleClinical, cosmetic and investigational dermatology2021

Prebiotic Colloidal Oat Supports the Growth of Cutaneous Commensal Bacteria Including

Fang Liu-Walsh, Neena K Tierney, James Hauschild, Allison K Rush, John Masucci, Gregory C Leo, Kimberly A Capone

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Skin Deep: The Potential of Microbiome Cosmetics.Journal of microbiology (Seoul, Korea) · 2024
    Review
  8. The Skin Microbiome and its Significance for Dermatologists.American journal of clinical dermatology · 2024
    Article
  9. Article
  10. The Interkingdom Interaction withJournal of microbiology and biotechnology · 2023
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Fang Liu-WalshJohnson & Johnson Consumer Inc., Skillman, NJ, USA.
Neena K TierneyJohnson & Johnson Consumer Inc., Skillman, NJ, USA.
James HauschildJohnson & Johnson Microbiological Quality & Sterility Assurance, Johnson & Johnson Inc., Raritan, NJ, USA.
Allison K RushJohnson & Johnson Consumer Inc., Skillman, NJ, USA.ORCID 0000-0001-8295-0816
John MasucciJanssen R&D Companies of Johnson & Johnson, Springhouse, PA, USA.
Gregory C LeoJanssen R&D Companies of Johnson & Johnson, Springhouse, PA, USA.
Kimberly A CaponeJohnson & Johnson Consumer Inc., Skillman, NJ, USA.
Johnson & Johnson (United States) · USSpringhouse · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple skin conditions have been associated with alterations in the diversity and composition of the skin microbiome, including dry skin and atopic dermatitis. In these conditions, a number of commensal skin bacteria have been implicated in supporting a healthy skin barrier, including

methodsSkin bacterial growth was assessed using the BacT/ALERT system.

resultsIn vitro, colloidal oat increased the growth rate of

conclusionColloidal oat directly affects the growth, metabolism, lactic acid production, and gene expression of skin commensal bacteria, as shown via in vitro studies. The increased production of lactic acid reflects clinical observations with colloidal oat-containing skin moisturizers. Our findings suggest a new mechanism for colloidal oat as a skin prebiotic, which may contribute to improvements in skin and microbiome diversity in various skin conditions, including dry/itchy skin and atopic dermatitis.

Indexed as

atopic dermatitiscolloidal oatdry skinS. epidermidisskin barrier functionskin microbiomeskin moisturizer

Identifiers

PMID33500646
PMCPMC7826061
OpenAlexW3123728092

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.